Dr. Mulhall answers: Not understanding the exact cause of the condition makes it very difficult to develop new treatments or a cure. However, at this point in time there are a number of centers in the world (mainly the USA) that are investigating the cause of Peyronie’s disease. Indeed, there has never been a time previously when as much interest has existed in Peyronie’s disease research. The single greatest barrier to curing Peyronie’s disease is the lack of research money available to conduct excellent research. Through APDA it is hoped that the NIH or other organizations will look more favorably on this condition.