General

I am a medical student and I’m interested in finding more about Peyronie’s disease. Is it possible to develop PD after transurethral resection of the prostate?

It is extremely unlikely that TURP is associated with PD. Given the number of TURPs that have been performed at least historically, we should have seen a signal of a link. Furthermore, in my patients who link the two together than man has a dorsal plaque which

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I have been diagnosed with Peyronie’s for 5 years. During this whole time, I have experience continual pain that diminishes with steroids or Torodal. This pain disrupts my normal life. Have you any comments or suggestions to help the pain to subside and is this much pain associated with PD?

Peyronie’s disease is a disorder of wound healing which often times will present with pain because of inflammation associated with the initial scarring process. The inflammation irritates the pain fibers which are typically activated when the penis becomes erect causing stretching of these nerve fibers. When the

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I have had a penile curvature for 2 years that also has great pain. Is it a normal side effect of PD to have pain this long or is there another cause to consider?

Peyronie’s disease is a disorder of wound healing which often times will present with pain because of inflammation associated with the initial scarring process. The inflammation irritates the pain fibers which are typically activated when the penis becomes erect causing stretching of these nerve fibers. When the

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Are you aware if a “flex sig” colon exam can bring about PD?

A flexible sigmoidoscopy is performed for evaluation of the rectum and lower sigmoid colon. This procedure, to my knowledge, has not been associated with triggering Peyronie’s disease as there is no direct trauma to the penis or the genitalia. Certainly, it is possible that any trauma in

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Has there been determined to be a link between PD and other pelvic disorders, such as prostatitis, interstitial cystitis, or epididymitis? Is it possible that such disorders could lead to Peyronie’s or that one could lead to a false diagnosis of the other?

This is an interesting question as the chronic pelvic pain disorders such as prostatitis and interstitial cystitis and possibly chronic orchialgia (testicular pain) appear to be linked to the concept of chronic pain where there is a central nervous system modification of nerve response. These are pain

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Do you recommend discontinuing the use of tobacco products prior to installing an implant? Will the smoking constrict blood flow and create any additional dangers?

Absolutely, tobacco use around the time of surgery will increase the risk of complications and may impede proper healing because of reduced blood flow. Tobacco intake in any form will cause blood vessels to constrict after acute use, but with chronic exposure tobacco will accelerate the aging

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I am a 19 year old man. I have not had sex yet but I notice a bend of 25 degrees towards the left and 30 degrees upwards when fully erect. There are no scars or lumps detected. Can PD affect younger men? Are these bends permanent?

Several studies have shown that 10% of the men presenting with PD are under 40 years old. Younger men with PD have also been shown to do well with non-surgical treatment presumably because the healing response is better in younger men. However, most men under 20 who

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Does PD cause sterilization?

There is no connection between sterilization and PD. If the deformity is so bad that it prevents vaginal penetration, conception will be compromised, but this does not make the man sterile.

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It seems that the onset of PD occurred within a few weeks of having a cystoscopy. Could this have been the factor in getting my PD?

Dr. Levine answers: It is unlikely that any type of urethral manipulation would trigger Peyronie’s disease unless it resulted in a downward or ventral bend of the penis. This would suggest that urethral trauma may have activated some inflammation and scarring on the undersurface of the penis

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Is there any association between Lexopro and the development of PD?

Dr. Levine answers: At this point there is no evidence of direct association with the use of any medication and Peyronie’s disease. Historically, articles suggested in association with various medications, but these were typically case reports and due to a lack of understanding of the disease process.

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