Vitamin E may be used on a daily basis, but not more than 400 mg. Again there is no evidence that vitamin E truly benefits Peyronie’s disease, but it may have some potential benefits as an antioxidant and to prevent prostate disease, in particular prostate cancer.
Read more →Nonsurgical Treatment
This is a good question, as collagenase is an enzyme which breaks down collagen which is the primary component of a Peyronie’s plaque. Collagenase has been studied since the early 1980s. Recently there has been increased interest in the use of collagenase as a treatment for Peyronie’s
Read more →No. There is no evidence that topical verapamil has any proven benefit. The only study, which has been done by a group independent from the manufacturer, demonstrated no evidence of penetration of the topical verapamil gel into the underlying plaque tissue. Therefore, until properly performed and validated
Read more →There is no long-term data on ultrasound therapy and no study done in a randomized, controlled fashion.
Read more →There are no known over-the-counter products of benefit in Peyronie’s disease. Most urologists know little about this condition and are generally not completely up-to-date on treatments and we suggest that you seek out a Peyronie’s disease expert for evaluation and a discussion of treatments.
Read more →Dr. Larry Levine from Chicago has shown very elegantly that the use of iontophoresis allows verapamil applied to the skin to be absorbed into the tunica albuginea. This is in direct contrast to the use of transdermal verapamil without iontophoresis, as it has been clearly shown that
Read more →Dr. Levine answers: I have no experience with the use of DMSO, alone or in combination, as a form of therapy for Peyronie’s disease. I am also not familiar with any medical studies demonstrating any benefit from using DMSO, apple cider vinegar and/or castor oil for Peyronie’s
Read more →Dr. Mulhall answers: I am not familiar with the specific product you mention, however, here is what we know about transdermal therapy. There is not a single medical paper in the literature on the effectiveness of transdermal verapamil (go to PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi) to search for papers on
Read more →Vitamin E is probably the oldest oral therapy used in the modern era for Peyronie’s disease. Unfortunately there are no well done controlled trials demonstrating any benefit, and in a small controlled trial performed in England, no benefit was noted with the use of vitamin E for
Read more →These agents are called nutriceuticals, that is, compounds purported to be drug like but “all natural”. These compounds are not under FDA control and therefore any claims can be made without substantiation. The nutriceutical subcommittee of the Sexual Medicine Society Of North America (www.smsna.org) recently declared that
Read more →