Nonsurgical Treatment

I have been diagnosed with PD by a urologist 3 months ago. I am 59. He has prescribed 800 IU of vitamin E daily & also Infam-away (a hi-potency enzyme formula) capsules 6 daily on a empty stomach. Nothing has helped after taking these medicines for 3 months. Erections are very painful and curvature has developed to the left. An indentation about 1 inch below the glans has also developed. He has basically told me that there is nothing else he can do. My primary care physician admits that this is a disease that not much is known as to the whys and what will work to help the pain and hopefully stop or reverse the curvature which at present is 30-40%. I was given a pain killer to help especially if erections get too painful. Are there any over-the-counter or on the internet medicines that may help?

There are no known over-the-counter products of benefit in Peyronie’s disease. Most urologists know little about this condition and are generally not completely up-to-date on treatments and we suggest that you seek out a Peyronie’s disease expert for evaluation and a discussion of treatments.

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There has been much discussion concerning the use of DMSO forums to treat PD, including a mixture of DMSO, apple cider vinegar and castor oil has been suggested. Can you share your opinion and possible recommendations for its use?

Dr. Levine answers: I have no experience with the use of DMSO, alone or in combination, as a form of therapy for Peyronie’s disease. I am also not familiar with any medical studies demonstrating any benefit from using DMSO, apple cider vinegar and/or castor oil for Peyronie’s

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I have been using transdermal verapamil 15% by www.pdlabs.net for the last 5 months with no visible results. They told me that the cream would remodel the plaque into healthy tissue and while they couldn’t use the word cure they assured me their patented delivery system resulted in proper absorption of the medicine while other compounds were ineffective. They claimed this was one of the main reasons for so much misinformation about it. What do you make of their claims?

Dr. Mulhall answers: I am not familiar with the specific product you mention, however, here is what we know about transdermal therapy. There is not a single medical paper in the literature on the effectiveness of transdermal verapamil (go to PubMed (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi) to search for papers on

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I just went to a urologist and he told me to take 400 IU of vitamin E for at least 6 months. Does Peyronie’s disease prevent the penis from hanging lower during the flaccid state? My penis is very short during flaccid. And also if the vitamin E works will my penis stretch to its full potential?

Vitamin E is probably the oldest oral therapy used in the modern era for Peyronie’s disease. Unfortunately there are no well done controlled trials demonstrating any benefit, and in a small controlled trial performed in England, no benefit was noted with the use of vitamin E for

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Is there any Peyronie’s research with regards to Serrapeptase? What about Natto, Nattokinase, or Buluoke for treatment of fibrin or PD?

These agents are called nutriceuticals, that is, compounds purported to be drug like but “all natural”. These compounds are not under FDA control and therefore any claims can be made without substantiation. The nutriceutical subcommittee of the Sexual Medicine Society Of North America (www.smsna.org) recently declared that

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