Vitamins/Herbal Supplements

Do you have any comment on the study of taking Co-Q10 to help Peyronie’s?

There was one study that was performed in Iran with questions as to the validity of the results. Therefore, since this is the only published study examining Co-Q10, no recommendations can be made. One thing that is clear though, is that there does not appear to be

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Is it safe to take L-arginine and low dose daily Cialis (2.5 or 5mg) at the same time? How long do you recommend I taking L-arginine? Is the recommended dose of L-arginine 1000mg twice a day or is it 500mg twice a day?

With respect to the L-arginine, the recommended dosing has been 1000 mg twice per day, but this is not based on any type of well-controlled trial. There are no reports of taking Cialis with L-arginine causing low blood pressure, but this is a possible side effect.

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I was taking a daily dose of 1000mg of vitamin C for years. Do you think this may have contributed to my Peyronie’s disease?

There is no evidence that taking vitamin C would contribute to developing Peyronie’s disease. In fact, there is really no evidence that any oral agents, supplements, or drugs are known to cause Peyronie’s disease.

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Will taking calcium pills for any length of time cause damage?

To my knowledge, there is no evidence that taking calcium, as a supplement would encourage calcification of a Peyronie’s plaque. This calcification of plaque is likely a genetically governed process, which is unlikely altered by taking extra calcium or no calcium at all.

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In November 2004, I noticed a small bending to the left of the penis. I am currently taking vitamin E 600 units daily and I rub hydrocortisone 2% on the penis every morning. Do you think that the bending will get worse or will it stop?

It may be that you have an early form of Peyronie’s disease, which is either spontaneously recovering which occurs in less than 10% of cases, or may be responding to the oral and topical medicines that you are using. Unfortunately, there is very little evidence that vitamin

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How long should I take the vitamin E?

Vitamin E may be used on a daily basis, but not more than 400 mg. Again there is no evidence that vitamin E truly benefits Peyronie’s disease, but it may have some potential benefits as an antioxidant and to prevent prostate disease, in particular prostate cancer.

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Will enzymes work in the treatment of Peyronie’s disease?

This is a good question, as collagenase is an enzyme which breaks down collagen which is the primary component of a Peyronie’s plaque. Collagenase has been studied since the early 1980s. Recently there has been increased interest in the use of collagenase as a treatment for Peyronie’s

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I have severe deformation from PD, do you think I should try topical Verapamil?

No. There is no evidence that topical verapamil has any proven benefit. The only study, which has been done by a group independent from the manufacturer, demonstrated no evidence of penetration of the topical verapamil gel into the underlying plaque tissue. Therefore, until properly performed and validated

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I have been diagnosed with PD by a urologist 3 months ago. I am 59. He has prescribed 800 IU of vitamin E daily & also Infam-away (a hi-potency enzyme formula) capsules 6 daily on a empty stomach. Nothing has helped after taking these medicines for 3 months. Erections are very painful and curvature has developed to the left. An indentation about 1 inch below the glans has also developed. He has basically told me that there is nothing else he can do. My primary care physician admits that this is a disease that not much is known as to the whys and what will work to help the pain and hopefully stop or reverse the curvature which at present is 30-40%. I was given a pain killer to help especially if erections get too painful. Are there any over-the-counter or on the internet medicines that may help?

There are no known over-the-counter products of benefit in Peyronie’s disease. Most urologists know little about this condition and are generally not completely up-to-date on treatments and we suggest that you seek out a Peyronie’s disease expert for evaluation and a discussion of treatments.

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