Signs And Symptoms

I have heard a lot about Peyronie’s disease, but nowhere did it mention if this is a temporary or permanent condition. Is it possible for the body to dissolve the tissue that causes the curvature?

Dr. Levine answers: Peyronie’s disease is a disorder of wound healing with unclear cause. Typically when it occurs, it will be associated with a lump, occasionally pain and deformity. Natural history studies have suggested that about 50% of men who come to see a physician will worsen

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Is there any way of determining exactly how long one has had PD?

Dr. Levine answers: This is a good question. For the man who develops acute onset of PD, the typical findings are pain in the penis, either followed by or preceded by the presence of a palpable nodule or lump, which is then followed by a shape deformity

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I’ve had Peyronie’s disease for about 6 years. I can still get adequate erections and achieve intromission. However, there appears to be loss of sensation on one side of the penis which makes it difficult to reach orgasm, causing frustration for me and my partner. Could this be treated and/or reversed?

Dr. Levine answers: Loss of sensation is an unusual complaint for men with Peyronie’s disease. But your situation may be because the deformity interferes with stimulation of the area on your penis which is important for sexual arousal. If indeed the curvature is responsible for the diminished

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Can Peyronie’s cause high elevated level of CPK?

Dr. Levine answers: I am not familiar with Peyronie’s disease causing any changes in CPK. This is usually due to muscle related injury, which is not considered a sequalae of Peyronie’s disease.

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My penis does not have a curvature. However, are these symptoms associated with PD — numbness and white spots on the tip of the glans and occasional numbness of the testicles. My erections are also not as stiff.

Dr. Levine answers: These are not symptoms of PD. A change in the sensation of the glans may be due to underlying medical problems such as diabetes which can affect the sensory nerves of the penis. Change in the color or pigmentation of the glans is usually

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Will I obtain benefits if I rub collagenase instead of hydrocortisone on the place I feel the damage?

Dr. Levine answers: If you can obtain collagenase, which to my knowledge is not at all available, it would be absolutely contraindicated to place this agent on the skin as it could cause a significant injury in that area. Injectable collagenase, in time will hopefully be available

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I have an extreme case of PD, upward and back. I have used treatments ranging from Potaba to verapamil alone or with DMSO topically. Any advice you can give for this extreme case of PD and any other steps to consider?

Dr. Levine answers: If you have severe PD which is compromising your sexual function and you have not responded to these topical or oral therapies, I would suggest that you speak to an authority in the treatment to Peyronie’s disease. There is a list of suggested physicians

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I am 23 years-old. I don’t get excited or develop an erection until I watch a porn movie. I have a slight bending towards the right and I feel that my erections are not hard and occur infrequently. Do I suffer from Peyronie’s disease, and is it recoverable?

Dr. Levine answers: This problem sounds more like primary erectile dysfunction, which may have a physical basis, but oftentimes could have a psychodynamic one as well. You might consider stopping masturbation and see if there is spontaneous recovery, but if not evaluation by an Urologist with a

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Can treatment options like injections of verapamil be just as effective if you wait too long for that treatment and the curvature is around 90 degrees?

Dr. Levine answers: This question will be answered in 2 parts. One pertains to the severity of curvature which at 90 degrees is certainly a severe curve and the other is the duration of disease and whether the scarring process is stable or still active. Published studies

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