Signs And Symptoms

I’m 56 and was diagnosed with PD 9 years ago. I am diabetic, and was also diagnosed with Dupuytren’s contracture. In the last few years, my erections have really shrunk. I used to have about a 6-inch erection now my erections are about the size of my thumb (both in length and thickness). My wife and I haven’t had sex in about 6 years and I can’t even discuss this with her. Over the last 13 months I have added Plavix, Toprol XL, and Zocor to the insulin I take. Is there anything that can help me or is there something else coming along in the next year or two?

You clearly have an advanced problem with fibrotic disorders including the Peyronie’s disease and Dupuytren’s contracture. The PD is likely causing the loss of elasticity of the penis and subsequent loss of length and girth. It is also likely that the combination of diabetes, elevated blood pressure,

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I have detected hard rings on my penis which are felt only during an erection. Peyronie’s disease has not been diagnosed. Can I stop any further deterioration since finding this early? What signs should I look for if this is indeed PD?

What you describe may be a variant of Peyronie’s disease, but to make the diagnosis the penis is typically evaluated in the flaccid condition, the glans is pulled out to stretch the penis and then the shaft can be palpated to identify the fibrotic scar tissue known

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When a man with Peyronie’s disease also has impotence what can be done?

Dr. Mulhall answers: The conventional wisdom has held that men with combined impotence (erectile dysfunction, or ED) and Peyronie’s disease are ideally treated with a penile implant (a plastic device placed within the penis that can be inflated for sex and deflated after sex). This paradigm has

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In your opinion, what is the best treatment to prevent fibrosis from spreading around the tunica or into the vascular tissue for a Peyronie’s disease patient?

At this point there is no recognized best treatment to prevent fibrosis from spreading within the tunica albuginea or into the vascular tissue of the penis for the man with PD. Recent research from California has suggested that increasing the amount of nitric oxide (NO) can act

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Is it possible to get stretch marks on the outer skin of the penis? I have developed two horizontal red “stripes” that resemble stretch marks. Is this Peyronie’s disease? What can I do to alleviate the problem? I am terrified that this will result in Peyronie’s disease.

Peyronie’s disease involves the jacket tissue which surrounds the vascular tissue of the penis. This jacket is known as the tunica albuginea and remains below the skin and subcutaneous tissues. Peyronie’s disease therefore does not affect the penile skin in any way. Therefore, any changes happening on

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Can you give us your professional opinion on the possibility of a cure anytime in the foreseeable future?

Dr. Mulhall answers: Not understanding the exact cause of the condition makes it very difficult to develop new treatments or a cure. However, at this point in time there are a number of centers in the world (mainly the USA) that are investigating the cause of Peyronie’s

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A read a piece saying that daily erections are crucial for oxygenation and to prevent collagen from occurring? Is lack of daytime erections (none at all) a problem? If so, what can I do about it?

Penile oxygenation is indeed crucial to maintain good vascular health within the penis. This is why we believe that men have nocturnal erectile activity. These erections occur due to a spontaneous reflex which happens anywhere from 2 to 7 times per night. This will in a sense

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I have PD and fortunately do not have difficulty with erection. I have heard about taking erectile dysfunction drugs like Viagra to promote “penile health.” Does this help?

At this time there is no clear evidence to show that Viagra enhances penile health on the long-term. The other PDE-5 inhibitors, including Levitra and Cialis, have also been shown to improve blood flow into the penis and there is some suggestion that long-term use of any

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Can PD explain why I have always had very little sensations in the skin of the penis? I have been going to different doctors for years about it, and now a urologist told me it might be related to PD. Is this a known phenomenon?

Dr. Mulhall answers: No. Men with sensory problems in their penis need neurologic evaluation using tests such as somatosensory evoked potentials to define if there is a physical nerve injury.

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I am 23 years old, and I think I have Peyronie’s. I have a significant bend and three inflamed soft scars on the right on the side of my shaft. The bend is about 45 degrees to the left and very apparent upon erection. However, I do not have any pain when I get an erection and the lumps are soft, not hard. I have been pretty stable with the condition for three years, but I am trying to find an alternative way to treat this. I have taken Potaba with no success. I am currently on vitamin E and I am noticing no difference. I read up on the serrapetase, nattokinase and bromelain for dissolving scar tissue. Is there anything I can do to help this condition?

There have been 2 reports on young men with Peyronie’s. These studies evaluated a large series of men and found that up to ten percent of those with Peyronie’s disease are under the age of 40. Therefore, this process can present in men anytime from his teens

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