In response to your answer in November 2003 regarding topical verapamil (TV), what is the likelihood of concentration in the tunica albuginea (TA) would be had the product been applied for a longer period of time, other than 1 day; say a week or a month, etc.?

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We know that TV is absorbed into the circulation as it appears in the urine of men who use so it is likely that all of the TV is removed from the skin by absorption into the circulation within hours. Therefore, a longer duration of application is unlikely to result in better tunical penetration. The use of iontophoresis can drive verapamil into the tunica however studies to prove that this results in deformity changes have not yet been conclusive.

Previous In one of your answers you say the following: “Indeed, if treatment is started early it may prevent progression of the condition and may result in less length loss.” So taking a typical case of a lump in the middle causing an upward bend in the penis, what exactly would you use as “treatment” that is recommended early on and what is early?
Next Iontophoresis treatment: Do you know of any other companies besides Physion that are offering this modality? I found numerous companies that make portable devices similar to Physion. Is their protocol machine different or is the iontophoresis basically the same?
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