Is it possible for PD sufferers to have flare-ups in pain at the plaque site (even when the penis is flaccid) for 10 to 20 years?

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It is generally believed that PD becomes stable somewhere between 12-18 months after its onset. Many patients in my practice stabilize within the first 6 months but rare patients continue to have pain for up to 2 years. It is not likely that the penile pain being experienced by you is related to the original plaque. It is either related to another plaque or some other cause. Seeing a urologist who has an interest of specializes in PD is worthwhile.