Dr. Levine answers: I have no experience with the use of DMSO, alone or in combination, as a form of therapy for Peyronie’s disease. I am also not familiar with any medical studies demonstrating any benefit from using DMSO, apple cider vinegar and/or castor oil for Peyronie’s disease. All of these may have some reported benefits with regards to treatment of scarring. But this type of therapy truly falls within the realm of complimentary alternative medicine with no evidence based medicine report to support their use. Therefore should anyone elect to use these types of alternative therapies, it is at their own risk, and likely with little benefit.