Dr. Mulhall answers: The conventional wisdom has held that men with combined impotence (erectile dysfunction, or ED) and Peyronie’s disease are ideally treated with a penile implant (a plastic device placed within the penis that can be inflated for sex and deflated after sex). This paradigm has more recently been challenged. Indeed, many men with ED can be well-treated using drug therapy such as pills (Viagra, Levitra, Cialis) or penile injections. If a man has curvature that is not severe enough to prevent him from being able to penetrate then it is possible to use one of the above drugs to help him regain his erection hardness. At the same time attention can be focused on treating the Peyronie’s disease (pain, deformity etc). In cases where the deformity prevents penetration ability then the patient will need to consider surgical correction of the penile deformity. Correction of the deformity and erection problems can be accomplished most easily by placing a penile implant. However, there are patients who can consider other forms of penile reconstructive surgery to correct the deformity and straighten their penis who can also use pills or injections to help their erections. However, to date, there has not been a medical study comparing these approaches.