Knowledge Base

Causes

• After a biking trauma I have erectile dysfunction and pain when sitting. Erections are rare without desire and my penis is curved and sticks to my body. I am 22, do I suffer from PD?
• Are you aware if a "flex sig" colon exam can bring about PD?
• Can hypertensions cause Peyronie's disease?
• Did my existing Dupuytren's contraction condition increase my possibility of PD because of the cystoscopy?
• Do you recommend discontinuing the use of tobacco products prior to installing an implant? Will the smoking constrict blood flow and create any additional dangers?
• Does PD cause sterilization?
• Has any correlation been shown (or link) between the onset of Peyronie's and the use of any drugs, ie, Lipitor, Tricor, Rogaine?
• Has there been determined to be a link between PD and other pelvic disorders, such as prostatitis, interstitial cystitis, or epididymitis? Is it possible that such disorders could lead to Peyronie's or that one could lead to a false diagnosis of the other?
• I am a 19 year old man. I have not had sex yet but I notice a bend of 25 degrees towards the left and 30 degrees upwards when fully erect. There are no scars or lumps detected. Can PD affect younger men? Are these bends permanent?
• I am a medical student and I'm interested in finding more about Peyronie's disease. Is it possible to develop PD after transurethral resection of the prostate?
• I contracted Dupuytren's contracture 30 years ago. Did having DC predispose me to PD?
• I had a piercing in my penis (a PA) a couple of years ago. When I had it stretched to 5 mm, it appears the "lump" in my penis and the bend occurred. Have you heard of this before? Is it coincidental?
• I have been diagnosed with Peyronie’s for 5 years. During this whole time, I have experience continual pain that diminishes with steroids or Torodal. This pain disrupts my normal life. Have you any comments or suggestions to help the pain to subside and is this much pain associated with PD?
• I have been riding a bicycle for 60+ years, and continue to ride daily. I often have penile numbness after a period of time in the saddle. Could this be a cause of PD, and cause further exacerbation of my PD? Do you have any recommendations on bicycle saddles, or bicycle types, that would hep reduce penile numbness/trauma? Thank you.
• I have had a penile curvature for 2 years that also has great pain. Is it a normal side effect of PD to have pain this long or is there another cause to consider?
• I was kicked in the penis six weeks ago. I was diagnosed with Peyronie's disease this week. I have not had intercourse in a year or more. Could the injury have caused the Peyronie's disease?
• In any of the cases you've seen, is stress indicated as a possible trigger for Peyronie's? I ask, because in me its appearance coincided with a very stressful period of my life.
• Is there a causal link between adolescent masturbation and PD?
• Is there any association between Lexopro and the development of PD?
• Is there any association of PD with use of ED drugs such as Cialis. Could taking Viagra and Cialis once or twice a month over 2 yrs have caused me to develop Peyronie's Disease?
• Is there any correlation between other autoimmune disorders, such as lichen planus for example, and the occurrence of PD, or the prognosis of the condition?
• It seems that the onset of PD occurred within a few weeks of having a cystoscopy. Could this have been the factor in getting my PD?
• Since trauma and micro-trauma are widely accepted as a major cause of PD, what is believed to be the level of risk from intralesional verapamil (ILV) treatments? Also, does the aging process make the tunica more subject to damage from ILV treatments?
• What are the implications of PD secondary to catheterization trauma as regards the causal factors of PD? Why would inflammation in the urethra lead to PD? Why would injury to a separated part of the penis find its way to the tunica?
• What causes waisting?
• What is the link between Peyronie's and Dupuytren's contracture?
Show all articles ( 21 ) Collapse Articles

• Drugs (Cialis, Viagra, Rogaine, etc)

  • Has any correlation been shown (or link) between the onset of Peyronie's and the use of any drugs, ie, Lipitor, Tricor, Rogaine?
  • Is there any association of PD with use of ED drugs such as Cialis. Could taking Viagra and Cialis once or twice a month over 2 yrs have caused me to develop Peyronie's Disease?

• Dupuytren's Disease

  • Did my existing Dupuytren's contraction condition increase my possibility of PD because of the cystoscopy?
  • I contracted Dupuytren's contracture 30 years ago. Did having DC predispose me to PD?
  • What is the link between Peyronie's and Dupuytren's contracture?

• General

  • Are you aware if a "flex sig" colon exam can bring about PD?
  • Do you recommend discontinuing the use of tobacco products prior to installing an implant? Will the smoking constrict blood flow and create any additional dangers?
  • Does PD cause sterilization?
  • Has there been determined to be a link between PD and other pelvic disorders, such as prostatitis, interstitial cystitis, or epididymitis? Is it possible that such disorders could lead to Peyronie's or that one could lead to a false diagnosis of the other?
  • I am a 19 year old man. I have not had sex yet but I notice a bend of 25 degrees towards the left and 30 degrees upwards when fully erect. There are no scars or lumps detected. Can PD affect younger men? Are these bends permanent?
  • I am a medical student and I'm interested in finding more about Peyronie's disease. Is it possible to develop PD after transurethral resection of the prostate?
  • I have been diagnosed with Peyronie’s for 5 years. During this whole time, I have experience continual pain that diminishes with steroids or Torodal. This pain disrupts my normal life. Have you any comments or suggestions to help the pain to subside and is this much pain associated with PD?
  • I have had a penile curvature for 2 years that also has great pain. Is it a normal side effect of PD to have pain this long or is there another cause to consider?
  • Is there a causal link between adolescent masturbation and PD?
  • Is there any association between Lexopro and the development of PD?
  • Is there any correlation between other autoimmune disorders, such as lichen planus for example, and the occurrence of PD, or the prognosis of the condition?
  • It seems that the onset of PD occurred within a few weeks of having a cystoscopy. Could this have been the factor in getting my PD?
  • What causes waisting?
  Show all articles ( 8 ) Collapse Articles

• Hypertension/Stress

  • Can hypertensions cause Peyronie's disease?
  • In any of the cases you've seen, is stress indicated as a possible trigger for Peyronie's? I ask, because in me its appearance coincided with a very stressful period of my life.
  • What are the implications of PD secondary to catheterization trauma as regards the causal factors of PD? Why would inflammation in the urethra lead to PD? Why would injury to a separated part of the penis find its way to the tunica?

• Trauma

  • After a biking trauma I have erectile dysfunction and pain when sitting. Erections are rare without desire and my penis is curved and sticks to my body. I am 22, do I suffer from PD?
  • I had a piercing in my penis (a PA) a couple of years ago. When I had it stretched to 5 mm, it appears the "lump" in my penis and the bend occurred. Have you heard of this before? Is it coincidental?
  • I have been riding a bicycle for 60+ years, and continue to ride daily. I often have penile numbness after a period of time in the saddle. Could this be a cause of PD, and cause further exacerbation of my PD? Do you have any recommendations on bicycle saddles, or bicycle types, that would hep reduce penile numbness/trauma? Thank you.
  • I was kicked in the penis six weeks ago. I was diagnosed with Peyronie's disease this week. I have not had intercourse in a year or more. Could the injury have caused the Peyronie's disease?
  • Since trauma and micro-trauma are widely accepted as a major cause of PD, what is believed to be the level of risk from intralesional verapamil (ILV) treatments? Also, does the aging process make the tunica more subject to damage from ILV treatments?

Future Treatments

• Can we generate our own new organ from DNA or stem cell therapy?
• Could you give your opinion regarding stem cell research as a solution? Are there any studies being done anywhere in the world with stem cell and Peyronie's?
• Do you have any current information on the use of stem cell therapy in treating PD?
• Given the advances in reconstructive surgery especially in light of the near full face transplant recently performed, what is the progress being made with respect to plaque excision and implantation of regenerated tunica albuginea for correction of Peyronie's disease?
• Will regeneration and transplantation of part or the entire penis occur in the near future?

• Stem Cell Research

  • Can we generate our own new organ from DNA or stem cell therapy?
  • Could you give your opinion regarding stem cell research as a solution? Are there any studies being done anywhere in the world with stem cell and Peyronie's?
  • Do you have any current information on the use of stem cell therapy in treating PD?
  • Given the advances in reconstructive surgery especially in light of the near full face transplant recently performed, what is the progress being made with respect to plaque excision and implantation of regenerated tunica albuginea for correction of Peyronie's disease?
  • Will regeneration and transplantation of part or the entire penis occur in the near future?

Nonsurgical Treatment

• A naturopathic doctor also recommends L-arginine for PD, but insists that a low dose will do nothing. No, he is not selling L-arginine. He recommends a very high dose — at least 3 grams per day and working up to 21 grams per day. Do you know of any risks to trying this?
• Are interferon injections as effective as verapamil injections?
• Are there any contraindications to using Adderall when one has a diagnosis of PD or if one were taking Trental and L-arginine as well as 10 mg of Cialis every other night?
• Besides a urologist manually checking the penis for scarring or nodules for possible Peyronie's disease, what other procedures (such as ultrasound) are more valid at determining if one does in fact have this disease? How accurate is checking for this disease manually?
• By reducing the plaque formations associated with Peyronie's disease is it possible to restore the elasticity of the penis or will the tissue remain in the non-elastic state due to the scarring?
• Can Botox work at relaxing and softening the plaque?
• Can pentoxifylline help with increasing blood flow when a man has PD? Also is Niacin also an alternative that might achieve any results?
• Can vacuum therapy cause damage?
• Can you give some more data about fexofenadine in PD treatment?
• Do lasers help with deformity at all?
• Do penile enlargement pills and patches work?
• Do penis stretchers actually help with Peyronie's disease?
• Do you have any comment on the study of taking Co-Q10 to help Peyronie's?
• Do you know of any doctors who give collagenase injections for Peyronie's disease?
• Does the use of vacuum therapy help eliminate the scarring which occurs from Peyronie's disease?
• Hand surgeons for Dupuytren's contractures have been successfully using an open percutaneous needle fasciotomy procedure instead of an open procedure. Why can't this closed percutaneous technique be a procedure used by urologists for Peyronie's patients?
• Have vacuum appliances had any effect on helping Peyronie's patients? Since there seems to be quite a controversy about the use of vacuum erection devices for PD therapy, would the doctor(s) provide any up to date information about the proper uses for the VEDs. Especially using the VEDs for PD.
• How do patients who have curvatures of the penis greater than 30 degrees do when the curvature involves just the distal end of the penis? Can it correct itself without treatment? What about vitamin E? Do we typically see worsening of the disease after a period of 12-18 months?
• How long should I take the vitamin E?
• I am 23 years old and having treatment of peyronies's disease applying verapamil gel as prescribed by doctor since 4 months. I still masturbate almost twice a week. Will this make my condition worse?
• I am 45, Peyronie's for 5 years, stable, curve about 75 degrees. I am able to have sexual intercourse, but I worry about getting worse over time. My urologist suggests I take 2 Pentox a day, Is this OK or should I take 3? I also worry about being on the Pentox for years, if I quit after one year will I experience any worsening? Will using Pentox mess with my Immune system? I suffer from lower than normal testosterone, so I get sick easily. Should vitamin D be taken with Pentox to help in immunity?
• I am 65 and was diagnosed with PD 18 months ago. I have a 50-degree upward curvature and some associated erectile dysfunction, but with Viagra I am still able to be sexually active. I plan to purchase the Fastsize Extender and use it in conjunction with L-arginine in hopes of reducing the degree of curvature. Is there a problem using L-argenine and Viagra together?
• I am a sixty-four year old white male living in the United Kingdom, six foot tall, twelve and a half stone in weight and I consider myself to be in good health. I am not on any medication; I exercise regularly, sleep well, eat healthily and had a good sex-life with my partner. At the end of March 2013 I was diagnosed with Peyronie's Disease. I have been offered a course of ESWT (Extracorporeal shock wave therapy). My question: This procedure ESWT, how effective is it in treating Peyronie's Disease, is it too early to do this procedure as it is only been six/seven months since the disease first started and how safe is the ESWT procedure? Many thanks for all the information the association has published, it has helped me enormously to come to terms with the disease.
• I am in physical therapy and want to do ultrasound for treatment of Peyronie's. What is the protocol, I have forgotten since school how many w/cm2 and what intensity to use. Also, do you use pulse or continuous ultrasound?
• I am looking for the best medical therapy for a moderate Peyronie’s case (no ED, age 30, healthy) and have questions about a combination Dr. Levine once proposed (PDE5 e.g. Sildenafil 25mg daily, L-arginine 500 mg twice daily, pentoxyfiline 400 mg thrice daily). 1. L-Arginine is known to be a precursor to nitric oxide. Why is that not contraindicated with Sildenafil ("no nitrics") 2. Pentox says it should not be combined with substances that lower the blood pressure. Any problem with Sildenafil?
• I developed a sudden onset of Peyronie's disease following treatment of blood pressure with Prinivil. This resulted in curvature to the left, as well as a 2-inch loss of length. If I were able to get my blood pressure down off of this medications would this help?
• I have a slight bend to the right and upward about 25 degrees and there is no pain. I cannot feel anything unusual along the shaft. My urologist has recommended transdermal verapamil. Can you comment on any recent information for this treatment?
• I have an aggressive case of PD and I am an avid bodybuilder and weight lifter. Will penile traction therapy work for me? I do not want to take any oral medications. What traction system holds the most promise?
• I have been considering ESWT treatment for Peyronie's disease but I would like to know about the percentage of successful treatment. I don't have a lot of pain with the erection but I have the curvature? I also take Viagra because of inadequate blood flow. Does the ESWT increase blood flow or does it just correct the curvature?
• I have been diagnosed with early stage PD (no noticeable curvature). I have been taking Potaba, acetyl-l carnitine and vitamin E for about a month with some moderate improvement in pain. I recently saw a specialist in PD who said I should be taking a combination of Trental, L-arginine and Viagra. Have you heard that the latter combination is effective? I am very concerned about taking Viagra on a daily basis and have not had any ED problems.
• I have been diagnosed with PD by a urologist 3 months ago. I am 59. He has prescribed 800 IU of vitamin E daily & also Infam-away (a hi-potency enzyme formula) capsules 6 daily on a empty stomach. Nothing has helped after taking these medicines for 3 months. Erections are very painful and curvature has developed to the left. An indentation about 1 inch below the glans has also developed. He has basically told me that there is nothing else he can do. My primary care physician admits that this is a disease that not much is known as to the whys and what will work to help the pain and hopefully stop or reverse the curvature which at present is 30-40%. I was given a pain killer to help especially if erections get too painful. Are there any over-the-counter or on the internet medicines that may help?
• I have been using transdermal verapamil 15% by www.pdlabs.net for the last 5 months with no visible results. They told me that the cream would remodel the plaque into healthy tissue and while they couldn't use the word cure they assured me their patented delivery system resulted in proper absorption of the medicine while other compounds were ineffective. They claimed this was one of the main reasons for so much misinformation about it. What do you make of their claims?
• I have had Peyronie's disease for 1 year and 10 months and just went through Intron A injections every 2 weeks for 3 months. I have not seen any change. The Peyronie's specialist wants to do a second wave of injections. If this did not work at all, do you think it is wise to go through a second injection battery?
• I have heard that vitamin E is the only known treatment. Is that correct? If so, can it be taken by injection for more effectiveness? Is there stem cell research going on for Peyronie's disease, and is it possible to get involved with it?
• I have Peyronie's disease now for 12 years. All the ED pills will give an erection, but I quickly lose it. Is there anything I can do or take so the blood stays trapped? A cock ring does not work.
• I have read that cortisone injections have been effective in some cases, is this so?
• I have seen literature describing the use of penis traction devices, such as the Pro-Extender, to treat Peyronie's. Unlike vacuum devices, these traction devices are used for 8-12 hours a day. What is your opinion on this approach?
• I have severe deformation from PD, do you think I should try topical Verapamil?
• I just went to a urologist and he told me to take 400 IU of vitamin E for at least 6 months. Does Peyronie's disease prevent the penis from hanging lower during the flaccid state? My penis is very short during flaccid. And also if the vitamin E works will my penis stretch to its full potential?
• I was taking a daily dose of 1000mg of vitamin C for years. Do you think this may have contributed to my Peyronie's disease?
• I'm a 57 year old physician with an inflammatory plaque in my mid shaft of the penis but no curvature yet. I've been using Caverject for about 5 years with no side effects and had some penile trauma about 2 months ago. I'm currently taking vitamin E daily and ibuprofen without any results yet. Would a trial of ultrasound therapy be worth considering?
• I've been using verapamil for over a year and seen great results but have reached a point now where the curve seems to not continue to heal. I'm about 70% cured and going for the full cure. Verapamil seems to cause irritation and redness, usually ten minutes after I apply it I take a shower and wash thoroughly to remove it, my pharmacist says it takes only 5 minutes to soak in. What can be done about this?
• I've recently completed iontophoresis with 25 treatments every other day. The verapamil dosage was 20 mg/ml, using a positive charge with IOMED delivery pads. I used the verapamil only and did not include the decadron as many pharmacists, and my doctor said you can't drive 2 drugs in with different charges (positive and negative). I saw absolutely no change in my condition, although I have lost size, and my penis seems to be hard when flaccid. Is there any advice you could give me now? I am going to try a decadron only sequence next as they said this works better on long standing scars and mine is 9 years old.
• If using the suggested modalities of treatment for Peyronie's disease, Would it help or hinder a person who is taking Coumadin for heart valve replacement?
• In addition to verapamil, colchicine has also been shown to affect the ability of fibroblasts to make collagen. Have studies ever been done to determine whether or not local colchicine delivered via intralesional injection would have results similar, or better, than that of verapamil? Presumably this could deliver the drug to the site of the plaque, but without the systemic ill effects secondary to ingestion of oral colchicine.
• In November 2004, I noticed a small bending to the left of the penis. I am currently taking vitamin E 600 units daily and I rub hydrocortisone 2% on the penis every morning. Do you think that the bending will get worse or will it stop?
• In one of your answers you say the following: "Indeed, if treatment is started early it may prevent progression of the condition and may result in less length loss." So taking a typical case of a lump in the middle causing an upward bend in the penis, what exactly would you use as "treatment" that is recommended early on and what is early?
• In response to your answer in November 2003 regarding topical verapamil (TV), what is the likelihood of concentration in the tunica albuginea (TA) would be had the product been applied for a longer period of time, other than 1 day; say a week or a month, etc.?
• Iontophoresis treatment: Do you know of any other companies besides Physion that are offering this modality? I found numerous companies that make portable devices similar to Physion. Is their protocol machine different or is the iontophoresis basically the same?
• Is acupuncture effective in treating Peyronie's disease?
• Is it possible for iontophoresis to soften or even change any calcification that may be present in the plaque?
• Is it possible that injecting human growth factor into the affected area of plaque would break down this fibrous tissue? Given that as a side effect for heart patients who have been administered this, had fibrous or fibrotic tissue broken down.
• Is it possible that the "injections" from using erection-inducing drugs caused my Peyronie's disease?
• Is it safe to take L-arginine and low dose daily Cialis (2.5 or 5mg) at the same time? How long do you recommend I taking L-arginine? Is the recommended dose of L-arginine 1000mg twice a day or is it 500mg twice a day?
• Is it true that PD plaque (scar tissue) needs to be visualized by an ultrasound in order to perform verapamil injections?
• Is there any exercise that can help straighten the curvature?
• Is there any Peyronie's research with regards to Serrapeptase? What about Natto, Nattokinase, or Buluoke for treatment of fibrin or PD?
• Many Peyronie's suffers use traction devices to straighten their penises. Do many use jelqing for straightening?
• My doctor has recommended that I purchase a vacuum pump. What does this pump look like and where can I buy it?
• Once Peyronie's is no longer diagnosed and the curvature remains, will traction reduce the curve?
• Peyrontin has been offered as an oral cure for Peyronie's disease. Has there been any research done on it? Is there any other recent research done on oral treatments?
• Please tell me what is the best treatment for Peyronie's? Each Urologist in my country of Iran has a different idea about curing this disease. Will you please send me the best possible and easiest way of treatment?
• There has been considerable discussion on various forums about the three cylinder vacuum erection device study being done in Birmingham, Alabama by the Birmingham Urology group. What is your best considered opinion about vacuum therapy, especially using the three cylinder VED, for PD symptoms? Also, what is your opinion of the hand manipulated jelqing or milking action being suggested for penile enhancement and/or enlargement?
• There has been much discussion concerning the use of DMSO forums to treat PD, including a mixture of DMSO, apple cider vinegar and castor oil has been suggested. Can you share your opinion and possible recommendations for its use?
• There have been 2 recent studies done on the effectiveness of traction devices at reducing curvature. Paolo Gontero, et al reported an average curvature reduction of 4 degrees. Levine, et al reported an average curvature reduction of 15 degrees. The duration of both studies was 6 months and the hours of use per day was similar. What accounts for the large difference in results between the 2 studies?
• There was a placebo-controlled study published in 2005 on Potaba which showed that this drug halted progression of Peyronie's. Based on this data for those who tolerate Potaba, would this not be a reasonable addition to a verapamil injection and/or verapamil iontophoresis regimen? Would there be any contraindications to this?
• What are the frequency and dosage characteristics of verapamil? Can injections cause further damage (plaque)?
• What are your thoughts on the upcoming collagenase injections that are supposed to be marketed in 2007-2008? Why weren't these injections pushed before, it seems like verapamil was the hot PD drug for injections and now you are hearing more and more about collagenase. What are your predictions on the efficacy of this type of treatment or feasibility?
• What are your thoughts on the use of topical verapamil application via iontophoresis?
• What can you say about Pentox (Trental) as a treatment?
• What do you think of the treatment where the plaque is broken down similar to kidney stones, with shock waves?
• What is pentoxifylline, L-arginine, and collagenase?
• What is the approximate cost of verapamil, botox, cologne injections? Are they covered by medicare?
• What is the latest and most successful treatment for Peyronie's disease?
• What is the prevailing opinion on the application of verapamil salves to the affected area (plaque)of PD? I could not find it in the treatment tab site/page.
• What is the proper procedure when using the 3-cylinder vacuum therapy device?
• What is your opinion about Dr. Paulo Egydios' technique?
• What is your opinion on the use of intralesional verapamil for young patients who have had the disease for over three years, but have little or no calcification in the plaque? If it is sensible to try verapamil, would it be better to use iontophoresis? Would traction therapy further enhance the benefits?
• What is your view of electromotive drug administration? There is a report of a small control group with reported positive effects in the treatment of PD.
• What's the latest thinking on the possible role of some medications and invasive urological procedures in triggering or aggravating Peyronie's disease? The link with cystoscopies and other invasive urological procedures was noted in at least one published report?
• When a plaque has calcified is it a waste of time and money to treat with intralesional verapamil or interferon injections?
• When talking about vacuum therapy for PD, is that the same as using a penis pump? Could using a penis pump cause more damage? Having used a penis pump, and now having PD, could it have helped to start Peyronie's?
• Why is the VED not recognized by most urologists as being a viable treatment for PD?
• Will 5 injections of cortisone to the affected part once a week be helpful, or cause more damage?
• Will enzymes work in the treatment of Peyronie's disease?
• Will liquid or oral chelation agents have any affect on PD, as it dissolves plaque in the arteries?
• Will taking calcium pills for any length of time cause damage?
Show all articles ( 82 ) Collapse Articles

• Extracorporeal shock wave therapy (ES)

  • Besides a urologist manually checking the penis for scarring or nodules for possible Peyronie's disease, what other procedures (such as ultrasound) are more valid at determining if one does in fact have this disease? How accurate is checking for this disease manually?
  • I am a sixty-four year old white male living in the United Kingdom, six foot tall, twelve and a half stone in weight and I consider myself to be in good health. I am not on any medication; I exercise regularly, sleep well, eat healthily and had a good sex-life with my partner. At the end of March 2013 I was diagnosed with Peyronie's Disease. I have been offered a course of ESWT (Extracorporeal shock wave therapy). My question: This procedure ESWT, how effective is it in treating Peyronie's Disease, is it too early to do this procedure as it is only been six/seven months since the disease first started and how safe is the ESWT procedure? Many thanks for all the information the association has published, it has helped me enormously to come to terms with the disease.
  • I am in physical therapy and want to do ultrasound for treatment of Peyronie's. What is the protocol, I have forgotten since school how many w/cm2 and what intensity to use. Also, do you use pulse or continuous ultrasound?
  • I have been considering ESWT treatment for Peyronie's disease but I would like to know about the percentage of successful treatment. I don't have a lot of pain with the erection but I have the curvature? I also take Viagra because of inadequate blood flow. Does the ESWT increase blood flow or does it just correct the curvature?
  • Is it possible for iontophoresis to soften or even change any calcification that may be present in the plaque?
  • What do you think of the treatment where the plaque is broken down similar to kidney stones, with shock waves?
  • What is your view of electromotive drug administration? There is a report of a small control group with reported positive effects in the treatment of PD.
  Show all articles ( 2 ) Collapse Articles

• General

  • A naturopathic doctor also recommends L-arginine for PD, but insists that a low dose will do nothing. No, he is not selling L-arginine. He recommends a very high dose — at least 3 grams per day and working up to 21 grams per day. Do you know of any risks to trying this?
  • By reducing the plaque formations associated with Peyronie's disease is it possible to restore the elasticity of the penis or will the tissue remain in the non-elastic state due to the scarring?
  • Do penile enlargement pills and patches work?
  • Hand surgeons for Dupuytren's contractures have been successfully using an open percutaneous needle fasciotomy procedure instead of an open procedure. Why can't this closed percutaneous technique be a procedure used by urologists for Peyronie's patients?
  • How do patients who have curvatures of the penis greater than 30 degrees do when the curvature involves just the distal end of the penis? Can it correct itself without treatment? What about vitamin E? Do we typically see worsening of the disease after a period of 12-18 months?
  • I am 45, Peyronie's for 5 years, stable, curve about 75 degrees. I am able to have sexual intercourse, but I worry about getting worse over time. My urologist suggests I take 2 Pentox a day, Is this OK or should I take 3? I also worry about being on the Pentox for years, if I quit after one year will I experience any worsening? Will using Pentox mess with my Immune system? I suffer from lower than normal testosterone, so I get sick easily. Should vitamin D be taken with Pentox to help in immunity?
  • I am 65 and was diagnosed with PD 18 months ago. I have a 50-degree upward curvature and some associated erectile dysfunction, but with Viagra I am still able to be sexually active. I plan to purchase the Fastsize Extender and use it in conjunction with L-arginine in hopes of reducing the degree of curvature. Is there a problem using L-argenine and Viagra together?
  • I am looking for the best medical therapy for a moderate Peyronie’s case (no ED, age 30, healthy) and have questions about a combination Dr. Levine once proposed (PDE5 e.g. Sildenafil 25mg daily, L-arginine 500 mg twice daily, pentoxyfiline 400 mg thrice daily). 1. L-Arginine is known to be a precursor to nitric oxide. Why is that not contraindicated with Sildenafil ("no nitrics") 2. Pentox says it should not be combined with substances that lower the blood pressure. Any problem with Sildenafil?
  • I have a slight bend to the right and upward about 25 degrees and there is no pain. I cannot feel anything unusual along the shaft. My urologist has recommended transdermal verapamil. Can you comment on any recent information for this treatment?
  • I have an aggressive case of PD and I am an avid bodybuilder and weight lifter. Will penile traction therapy work for me? I do not want to take any oral medications. What traction system holds the most promise?
  • I have been diagnosed with early stage PD (no noticeable curvature). I have been taking Potaba, acetyl-l carnitine and vitamin E for about a month with some moderate improvement in pain. I recently saw a specialist in PD who said I should be taking a combination of Trental, L-arginine and Viagra. Have you heard that the latter combination is effective? I am very concerned about taking Viagra on a daily basis and have not had any ED problems.
  • I have heard that vitamin E is the only known treatment. Is that correct? If so, can it be taken by injection for more effectiveness? Is there stem cell research going on for Peyronie's disease, and is it possible to get involved with it?
  • In one of your answers you say the following: "Indeed, if treatment is started early it may prevent progression of the condition and may result in less length loss." So taking a typical case of a lump in the middle causing an upward bend in the penis, what exactly would you use as "treatment" that is recommended early on and what is early?
  • Is acupuncture effective in treating Peyronie's disease?
  • Is it true that PD plaque (scar tissue) needs to be visualized by an ultrasound in order to perform verapamil injections?
  • Is there any exercise that can help straighten the curvature?
  • Many Peyronie's suffers use traction devices to straighten their penises. Do many use jelqing for straightening?
  • My doctor has recommended that I purchase a vacuum pump. What does this pump look like and where can I buy it?
  • Once Peyronie's is no longer diagnosed and the curvature remains, will traction reduce the curve?
  • Peyrontin has been offered as an oral cure for Peyronie's disease. Has there been any research done on it? Is there any other recent research done on oral treatments?
  • Please tell me what is the best treatment for Peyronie's? Each Urologist in my country of Iran has a different idea about curing this disease. Will you please send me the best possible and easiest way of treatment?
  • There have been 2 recent studies done on the effectiveness of traction devices at reducing curvature. Paolo Gontero, et al reported an average curvature reduction of 4 degrees. Levine, et al reported an average curvature reduction of 15 degrees. The duration of both studies was 6 months and the hours of use per day was similar. What accounts for the large difference in results between the 2 studies?
  • What is the latest and most successful treatment for Peyronie's disease?
  • What is your opinion about Dr. Paulo Egydios' technique?
  • What is your opinion on the use of intralesional verapamil for young patients who have had the disease for over three years, but have little or no calcification in the plaque? If it is sensible to try verapamil, would it be better to use iontophoresis? Would traction therapy further enhance the benefits?
  • When a plaque has calcified is it a waste of time and money to treat with intralesional verapamil or interferon injections?
  • Why is the VED not recognized by most urologists as being a viable treatment for PD?
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• Injections

  • Are interferon injections as effective as verapamil injections?
  • Can Botox work at relaxing and softening the plaque?
  • Do you know of any doctors who give collagenase injections for Peyronie's disease?
  • I have had Peyronie's disease for 1 year and 10 months and just went through Intron A injections every 2 weeks for 3 months. I have not seen any change. The Peyronie's specialist wants to do a second wave of injections. If this did not work at all, do you think it is wise to go through a second injection battery?
  • I have read that cortisone injections have been effective in some cases, is this so?
  • In addition to verapamil, colchicine has also been shown to affect the ability of fibroblasts to make collagen. Have studies ever been done to determine whether or not local colchicine delivered via intralesional injection would have results similar, or better, than that of verapamil? Presumably this could deliver the drug to the site of the plaque, but without the systemic ill effects secondary to ingestion of oral colchicine.
  • Is it possible that injecting human growth factor into the affected area of plaque would break down this fibrous tissue? Given that as a side effect for heart patients who have been administered this, had fibrous or fibrotic tissue broken down.
  • Is it possible that the "injections" from using erection-inducing drugs caused my Peyronie's disease?
  • What are the frequency and dosage characteristics of verapamil? Can injections cause further damage (plaque)?
  • What are your thoughts on the upcoming collagenase injections that are supposed to be marketed in 2007-2008? Why weren't these injections pushed before, it seems like verapamil was the hot PD drug for injections and now you are hearing more and more about collagenase. What are your predictions on the efficacy of this type of treatment or feasibility?
  • Will 5 injections of cortisone to the affected part once a week be helpful, or cause more damage?
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• Medication

  • Are there any contraindications to using Adderall when one has a diagnosis of PD or if one were taking Trental and L-arginine as well as 10 mg of Cialis every other night?
  • Can pentoxifylline help with increasing blood flow when a man has PD? Also is Niacin also an alternative that might achieve any results?
  • Can you give some more data about fexofenadine in PD treatment?
  • Do lasers help with deformity at all?
  • I developed a sudden onset of Peyronie's disease following treatment of blood pressure with Prinivil. This resulted in curvature to the left, as well as a 2-inch loss of length. If I were able to get my blood pressure down off of this medications would this help?
  • I have Peyronie's disease now for 12 years. All the ED pills will give an erection, but I quickly lose it. Is there anything I can do or take so the blood stays trapped? A cock ring does not work.
  • I've been using verapamil for over a year and seen great results but have reached a point now where the curve seems to not continue to heal. I'm about 70% cured and going for the full cure. Verapamil seems to cause irritation and redness, usually ten minutes after I apply it I take a shower and wash thoroughly to remove it, my pharmacist says it takes only 5 minutes to soak in. What can be done about this?
  • I've recently completed iontophoresis with 25 treatments every other day. The verapamil dosage was 20 mg/ml, using a positive charge with IOMED delivery pads. I used the verapamil only and did not include the decadron as many pharmacists, and my doctor said you can't drive 2 drugs in with different charges (positive and negative). I saw absolutely no change in my condition, although I have lost size, and my penis seems to be hard when flaccid. Is there any advice you could give me now? I am going to try a decadron only sequence next as they said this works better on long standing scars and mine is 9 years old.
  • If using the suggested modalities of treatment for Peyronie's disease, Would it help or hinder a person who is taking Coumadin for heart valve replacement?
  • In response to your answer in November 2003 regarding topical verapamil (TV), what is the likelihood of concentration in the tunica albuginea (TA) would be had the product been applied for a longer period of time, other than 1 day; say a week or a month, etc.?
  • There was a placebo-controlled study published in 2005 on Potaba which showed that this drug halted progression of Peyronie's. Based on this data for those who tolerate Potaba, would this not be a reasonable addition to a verapamil injection and/or verapamil iontophoresis regimen? Would there be any contraindications to this?
  • What can you say about Pentox (Trental) as a treatment?
  • What is pentoxifylline, L-arginine, and collagenase?
  • What is the approximate cost of verapamil, botox, cologne injections? Are they covered by medicare?
  • What is the prevailing opinion on the application of verapamil salves to the affected area (plaque)of PD? I could not find it in the treatment tab site/page.
  • What's the latest thinking on the possible role of some medications and invasive urological procedures in triggering or aggravating Peyronie's disease? The link with cystoscopies and other invasive urological procedures was noted in at least one published report?
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• Nutraceuticals

  • Is there any Peyronie's research with regards to Serrapeptase? What about Natto, Nattokinase, or Buluoke for treatment of fibrin or PD?
  • Will liquid or oral chelation agents have any affect on PD, as it dissolves plaque in the arteries?

• Traction devices

  • Articles coming soon

• Tropical Treatment

  • I am 23 years old and having treatment of peyronies's disease applying verapamil gel as prescribed by doctor since 4 months. I still masturbate almost twice a week. Will this make my condition worse?

• Vacuum pumps

  • Can vacuum therapy cause damage?
  • Do penis stretchers actually help with Peyronie's disease?
  • Does the use of vacuum therapy help eliminate the scarring which occurs from Peyronie's disease?
  • Have vacuum appliances had any effect on helping Peyronie's patients? Since there seems to be quite a controversy about the use of vacuum erection devices for PD therapy, would the doctor(s) provide any up to date information about the proper uses for the VEDs. Especially using the VEDs for PD.
  • I have seen literature describing the use of penis traction devices, such as the Pro-Extender, to treat Peyronie's. Unlike vacuum devices, these traction devices are used for 8-12 hours a day. What is your opinion on this approach?
  • Iontophoresis treatment: Do you know of any other companies besides Physion that are offering this modality? I found numerous companies that make portable devices similar to Physion. Is their protocol machine different or is the iontophoresis basically the same?
  • There has been considerable discussion on various forums about the three cylinder vacuum erection device study being done in Birmingham, Alabama by the Birmingham Urology group. What is your best considered opinion about vacuum therapy, especially using the three cylinder VED, for PD symptoms? Also, what is your opinion of the hand manipulated jelqing or milking action being suggested for penile enhancement and/or enlargement?
  • What is the proper procedure when using the 3-cylinder vacuum therapy device?
  • When talking about vacuum therapy for PD, is that the same as using a penis pump? Could using a penis pump cause more damage? Having used a penis pump, and now having PD, could it have helped to start Peyronie's?
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• Vitamins/Herbal Supplements

  • Do you have any comment on the study of taking Co-Q10 to help Peyronie's?
  • How long should I take the vitamin E?
  • I have been diagnosed with PD by a urologist 3 months ago. I am 59. He has prescribed 800 IU of vitamin E daily & also Infam-away (a hi-potency enzyme formula) capsules 6 daily on a empty stomach. Nothing has helped after taking these medicines for 3 months. Erections are very painful and curvature has developed to the left. An indentation about 1 inch below the glans has also developed. He has basically told me that there is nothing else he can do. My primary care physician admits that this is a disease that not much is known as to the whys and what will work to help the pain and hopefully stop or reverse the curvature which at present is 30-40%. I was given a pain killer to help especially if erections get too painful. Are there any over-the-counter or on the internet medicines that may help?
  • I have been using transdermal verapamil 15% by www.pdlabs.net for the last 5 months with no visible results. They told me that the cream would remodel the plaque into healthy tissue and while they couldn't use the word cure they assured me their patented delivery system resulted in proper absorption of the medicine while other compounds were ineffective. They claimed this was one of the main reasons for so much misinformation about it. What do you make of their claims?
  • I have severe deformation from PD, do you think I should try topical Verapamil?
  • I just went to a urologist and he told me to take 400 IU of vitamin E for at least 6 months. Does Peyronie's disease prevent the penis from hanging lower during the flaccid state? My penis is very short during flaccid. And also if the vitamin E works will my penis stretch to its full potential?
  • I was taking a daily dose of 1000mg of vitamin C for years. Do you think this may have contributed to my Peyronie's disease?
  • I'm a 57 year old physician with an inflammatory plaque in my mid shaft of the penis but no curvature yet. I've been using Caverject for about 5 years with no side effects and had some penile trauma about 2 months ago. I'm currently taking vitamin E daily and ibuprofen without any results yet. Would a trial of ultrasound therapy be worth considering?
  • In November 2004, I noticed a small bending to the left of the penis. I am currently taking vitamin E 600 units daily and I rub hydrocortisone 2% on the penis every morning. Do you think that the bending will get worse or will it stop?
  • Is it safe to take L-arginine and low dose daily Cialis (2.5 or 5mg) at the same time? How long do you recommend I taking L-arginine? Is the recommended dose of L-arginine 1000mg twice a day or is it 500mg twice a day?
  • There has been much discussion concerning the use of DMSO forums to treat PD, including a mixture of DMSO, apple cider vinegar and castor oil has been suggested. Can you share your opinion and possible recommendations for its use?
  • What are your thoughts on the use of topical verapamil application via iontophoresis?
  • Will enzymes work in the treatment of Peyronie's disease?
  • Will taking calcium pills for any length of time cause damage?
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Sex and Masterbation

• I am 23 years old and having treatment of Peyronie’s disease applying verapamil gel as prescribed by doctor since 4 months. I still masturbate almost twice a week. Will this make my condition worse?
• I live in Romania: My penis has a downward bend, something like a banana. I don't feel any scar tissue, and I don't have erection problems. I am 19 and I have a girlfriend, but we haven't been able to have sex. Could this be Peyronie's disease?
• Is it common for a Peyronie's patient to have no sex drive, become depressed and impotent?
• Is it necessary that the full part of the penis be inserted into the vagina?
• My boyfriend, age 52, cannot reach orgasm during intercourse and both of us work very hard to achieve this. It usually takes about 30 minutes of masturbation after sex and oral sex. His penis is somewhat cobra shaped and just a little bent. Frequently during intercourse or oral sex he will lose his erection. What could be causing this?
• My penis has a curvature towards the right when erect. It has a deviation at the base, as well. There is no pain when erect or flaccid. I had sexual intercourse, but only a part of my penis got inserted. Is this a problem?
• My penis is always bent to the left; it is almost a 35-degree curve, 1 inch from the base of the penis. Is it Peyronie's or something else? Will I be able to have intercourse properly or is it a severe problem? Are you aware of any physician in Pakistan (Lahore), who is experienced with Peyronie's disease?
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• General

  • I am 23 years old and having treatment of Peyronie’s disease applying verapamil gel as prescribed by doctor since 4 months. I still masturbate almost twice a week. Will this make my condition worse?
  • Is it necessary that the full part of the penis be inserted into the vagina?
  • My penis has a curvature towards the right when erect. It has a deviation at the base, as well. There is no pain when erect or flaccid. I had sexual intercourse, but only a part of my penis got inserted. Is this a problem?
  • My penis is always bent to the left; it is almost a 35-degree curve, 1 inch from the base of the penis. Is it Peyronie's or something else? Will I be able to have intercourse properly or is it a severe problem? Are you aware of any physician in Pakistan (Lahore), who is experienced with Peyronie's disease?

• Sex

  • I live in Romania: My penis has a downward bend, something like a banana. I don't feel any scar tissue, and I don't have erection problems. I am 19 and I have a girlfriend, but we haven't been able to have sex. Could this be Peyronie's disease?
  • My boyfriend, age 52, cannot reach orgasm during intercourse and both of us work very hard to achieve this. It usually takes about 30 minutes of masturbation after sex and oral sex. His penis is somewhat cobra shaped and just a little bent. Frequently during intercourse or oral sex he will lose his erection. What could be causing this?

• Sex Drive

  • Is it common for a Peyronie's patient to have no sex drive, become depressed and impotent?

Signs and Symptoms

• A read a piece saying that daily erections are crucial for oxygenation and to prevent collagen from occurring? Is lack of daytime erections (none at all) a problem? If so, what can I do about it?
• After a physical exam including a chemically induced erection, I've been told by my urologist that the next step is a Corpora cavernosagram to determine the cause of my peyronies. Is this a common procedure in diagnosing peyronies? Can sonography be used instead?
• Along with the indentation, and the lump when I am flaccid, I also have trouble maintaining fuller erections, and I have noticed pain at times even when flaccid. Is it safe to try and maintain erections, masturbate and/or have sex?
• Although we are careful, my wife is experiencing difficulty with yeast infections. My PD curvature is about 90 degrees. Is PD the cause of this?
• Are there any foods or drinks (coffee, tea, alcohol) that PD sufferers should eliminate? Are there any food or drinks known to help the condition?
• As a spouse of a PD patient, what is the best way to approach the "inadequate" mental state my husband experiences — ignore, encourage, be candid, recommend medical treatment?
• Can a condom that is too tight, which was left on while asleep cause an hourglass deformity? Could this hourglass shape be the beginning of PD?
• Can PD explain why I have always had very little sensations in the skin of the penis? I have been going to different doctors for years about it, and now a urologist told me it might be related to PD. Is this a known phenomenon?
• Can Peyronie's cause high elevated level of CPK?
• Can Peyronie's disease occur a year after injury to the penis?
• Can treatment options like injections of verapamil be just as effective if you wait too long for that treatment and the curvature is around 90 degrees?
• Can you give us your professional opinion on the possibility of a cure anytime in the foreseeable future?
• Does penile cancer also produce the plaque like growths in the penis shaft like Peyronie's disease?
• How long is the inflammatory period of Peyronie's before a hard plaque can be detected?
• I am 22. When I see my erect penis, it is curved to the left (slight curve). I feel no pain or lumps during masturbation. Should I seek treatment?
• I am 23 years old, and I think I have Peyronie's. I have a significant bend and three inflamed soft scars on the right on the side of my shaft. The bend is about 45 degrees to the left and very apparent upon erection. However, I do not have any pain when I get an erection and the lumps are soft, not hard. I have been pretty stable with the condition for three years, but I am trying to find an alternative way to treat this. I have taken Potaba with no success. I am currently on vitamin E and I am noticing no difference. I read up on the serrapetase, nattokinase and bromelain for dissolving scar tissue. Is there anything I can do to help this condition?
• I am 23 years-old. I don't get excited or develop an erection until I watch a porn movie. I have a slight bending towards the right and I feel that my erections are not hard and occur infrequently. Do I suffer from Peyronie's disease, and is it recoverable?
• I am 25 years old, i have noticed my flaccid bend and have noticed hard plaques mainly on sides but sometimes the whole shaft seems hard when flaccid, my penis had gone a yellow colour and i am finding it very difficult to get erections when i do they are not ridgid, my flaccid keeps going really small an thin then it is large like rubber. My whole penis feels like rubber even when erect, i seem to be losing size will i get it back considering i am only 25
• I am 25 years old, I have noticed my flaccid bend and have noticed hard plaques mainly on sides but sometimes the whole shaft seems hard when flaccid, my penis had gone a yellow color and I am finding it very difficult to get erections. When I do they are not rigid, my flaccid keeps going really small and thin then it is largely like rubber. My whole penis feels like rubber even when erect, I seem to be losing size will I get it back considering I am only 25.
• I am 36 years old, I am able to get an erection, but it does not appear to have the same shape when I am lying on back, and when I try to correct this, it hurts. What can I do?
• I am 38 and have a 30-degree ventral and 45-degree left curvature with moderate to severe pain and discomfort. I do not recall a time when I did not have this curvature and therefore believe I have a congenital curvature rather than Peyronie's disease. It appears that men with congenital curvature rarely experience pain. Is it normal to have pain with congenital curvature, and is it possible and/or likely to have Peyronie's disease and congenital curvature?
• I am 50 years old and recently diagnosed with Peyronie's. I've been to 2 urologists, tried Potaba (stopped; too many side effects) and using verapamil gel at night. Surgery was also recommended. I've done some research and have seen the Extender. Does this work? I'm getting mixed reviews. I have a 30-40% downward curve.
• I am a 45 year old man. I have had Peyronie's disease for about a year and a half. It bothers me more than I can express. The glans is smaller now and it is embarrassing in daylight. I know it must sound trivial, given the true horrors in the world, but making love is one of the things I was really good at. Can you help me?
• I appear to have an unusual form of PD. I was diagnosed by my Urologist as having PD at the base of the penis near the scrotum. I do not have deformity or bend, but I do have a soft end to the penis. Why is this occurring?
• I do not know if I should see an urologist. I have erection problems. I still get nighttime and morning erections. However, I have trouble during intercourse. My erection points straight down. If I pull it to stand up, there is tension.
• I experience premature ejaculation and in addition, when I urinate it flows out in different directions. Could PD be the cause of both of these effects?
• I first noticed my symptoms only about 3 months ago (painful erections, hard nodule under the skin when flaccid) and am currently in the "active" phase of the disease. Is there anything I should or should not be doing during this phase in order to minimize the eventual resulting curvature? It's only slightly noticeable (approx. 5-10%) and I'd like it to stay that way.
• I had surgery (temporalis fascia graft) last summer. My penis is approx 3 inches in length. Before Peyronie's it was 7 inches. I still have the curve and use the Fastrack traction and soma pump. Using both has improved the use of the traction device because it enlarges the gland tor the device to hold onto the penis. However, after a month of using it about 2 hours a day, I have noticed that the plague seems softer but my penis still has a bend and continues to be short. Will this improve with consistent use?
• I have a slight curvature upward, a slight indentation in the middle of my shaft, and a small hard spot at the base. The hard spot and the pain started in the middle of the shaft, but have moved progressively to the base. Is this common?
• I have an extreme case of PD, upward and back. I have used treatments ranging from Potaba to verapamil alone or with DMSO topically. Any advice you can give for this extreme case of PD and any other steps to consider?
• I have been experiencing Peyronie's disease for the last 6 months or so. Currently, the bend is about 30 degrees. The scar is on the right of upper part of penis, leading to curvature towards right side. Continuous pain is associated even when it is flaccid. When erected, it remains the same and becomes more precise at the point of scar. When once in a blue moon the pain is not present, I feel sexual desire. Otherwise it is not that much intense. Moreover it has been superimposed by severe depression. Would you suggest something to get around it? Especially pain associated with it as it has made my life miserable.
• I have detected hard rings on my penis which are felt only during an erection. Peyronie's disease has not been diagnosed. Can I stop any further deterioration since finding this early? What signs should I look for if this is indeed PD?
• I have had PD for 10 months, with onset of curvature for 1 month and painful erections for 2 months. The curvature is 45 degrees dorsally and only at the end of the penis. The erections are strong, except for the distal third which is somewhat compromised. I am wondering whether my progression time line is faster than what I have read. I am 55 and I am worried that my condition will get worse or will it stabilize as it currently exists.
• I have had Peyronie's disease for 7 years and have recently noticed my penis shrinking in the flaccid state and becoming hard all over. When I get an erection my penis is bent 45 degrees to the right and when semi-erect it won't get fully hard. Is the scar preventing the corpus cavernosum from expanding or is the corpus cavernosum actually turning into fibrous tissue as well? What is the cause of this shrinkage effect?
• I have heard a lot about Peyronie's disease, but nowhere did it mention if this is a temporary or permanent condition. Is it possible for the body to dissolve the tissue that causes the curvature?
• I have just recently had an ultrasound scan and was told I have 7 plaques I have been told I have Peyronie's is this common to have 7 lumps as I don't know what to expect
• I have PD and fortunately do not have difficulty with erection. I have heard about taking erectile dysfunction drugs like Viagra to promote "penile health." Does this help?
• I recently developed some curving in my penis. The penis is slightly curved even when not erect or aroused. Also there is some difficulty in urination. How likely is it that this is PD? Also should I completely stop masturbation?
• I suffered a penile injury six years ago and was diagnosed with Peyronie’s but since then have been told that I am healed. I continue to see a deformity on and off. Is this permanent or will this too eventually go away.
• I suffered a penile injury six years ago and was diagnosed with peyronies but since then have been told that I am healed. I continue to see a deformity on and off. Is this permanent or will this too eventually go away.
• I was diagnosed in 2000 with PD. My original doctor suggested I let time pass and see what happens. Luckily, I listened to others and went to a specialist. I was treated with medicine for a year and the pain eventually went away. About 3 weeks ago, I began noticing a burning pain, but it had come from time to time as I healed, but I have no other problems. My question is, can the pain that I am feeling now be the result of some remaining scar tissue loosening, or am I headed for another bout of PD?
• I was diagnosed with PD about 2.5 years ago. Today the pain is gone, and I have sex although my penis is never as hard as it was before. I was wondering what were the chances, if any, of the PD recurring?
• I'm 56 and was diagnosed with PD 9 years ago. I am diabetic, and was also diagnosed with Dupuytren's contracture. In the last few years, my erections have really shrunk. I used to have about a 6-inch erection now my erections are about the size of my thumb (both in length and thickness). My wife and I haven't had sex in about 6 years and I can't even discuss this with her. Over the last 13 months I have added Plavix, Toprol XL, and Zocor to the insulin I take. Is there anything that can help me or is there something else coming along in the next year or two?
• I'm 65, have had minor PD symptoms in the way of excessive swelling during erection & slight pain and slight curvature of the tip of the penis beginning about 6 months ago with no injury as the cause. My urologist detected a slight mass at the base of my penis on the top side. I have a history of keloid scarring from two surgeries and successfully reduced scarring to minimum by repetitive, aggressive massaging of the scars. Might this work with PD?
• I've had Peyronie's disease for about 6 years. I can still get adequate erections and achieve intromission. However, there appears to be loss of sensation on one side of the penis which makes it difficult to reach orgasm, causing frustration for me and my partner. Could this be treated and/or reversed?
• In young men, once PD enters the chronic phase, can it convert back to the acute phase resulting in new plaque?
• In your opinion, what is the best treatment to prevent fibrosis from spreading around the tunica or into the vascular tissue for a Peyronie's disease patient?
• Is it possible for PD sufferers to have flare-ups in pain at the plaque site (even when the penis is flaccid) for 10 to 20 years?
• Is it possible to get stretch marks on the outer skin of the penis? I have developed two horizontal red "stripes" that resemble stretch marks. Is this Peyronie's disease? What can I do to alleviate the problem? I am terrified that this will result in Peyronie's disease.
• Is there any data from the pilot study performed by Dr. Levine on traction therapy with respect to patient's response tracked during the 6-month study?
• Is there any way of determining exactly how long one has had PD?
• My bend is about 35% down and slightly to the right. Though I have never felt a plaque of any kind, there is a small indent in the right side close to the base. I do not experience pain unless I undergo more than one erection in a short amount of time. In the past few years, I have noticed a definite decrease in size, strength, stamina and intensity of climax. My urine flow has decreased and my penis in the flaccid state is both smaller and more limp than it ever has been. I can achieve erections, but for a short period of time and with little to no build up to a less than satisfying orgasm. These problems seem to be worsening. I am 27 and do not want the condition to worsen. Does this sound like a specific condition or symptom of PD and if so, what can I do?
• My erections seem shorter than normal; the penis seems more slender and the head of the penis never gets hard or firm. I assumed I had Peyronie's disease, but the doctor said there was no hard spot which apparently is typical. I am wondering if there could be another cause such as low testosterone.
• My husband has had Peyronie's disease for 16 months now. Will the pain during ejaculation ever go away?
• My penis does not have a curvature. However, are these symptoms associated with PD — numbness and white spots on the tip of the glans and occasional numbness of the testicles. My erections are also not as stiff.
• Since I presented with PD about 6 years ago, I have observed a profound change in the appearance of my flaccid penis. What use to hang several inches outside of my body has shriveled up and retracted, and now resides close to my pubic hair. In addition, many of the veins and capillaries that once were plainly visible on my erect penis seem to have disappeared; some of those capillaries or small veins were very painful prior to their apparent demise. My flaccid penis often feels colder than it once did. Are all of these symptoms consistent with PD, or could other medical pathology be responsible for these changes? If so, what might they be?
• What is the best and the most accurate test to evaluate any scarring or scar tissue in the tunica to determine whether it is considered PD? Do you recommend chronic use of small doses of Viagra as an anti-fibrotic regimen? What do you think about using Trental in conjunction with nightly use of Viagra?
• When a man with Peyronie's disease also has impotence what can be done?
• When I am erect only the head of my penis tilts to the right while the shaft remains straight. Is this PD?
• When I get an erection, on the left side of my penis there are 2 very visible band or lumps that are palpable, less than 3 cm, that appear to be in the erectile tissue, that span across the left side of the shaft which become bigger and harder when I get an erection and smaller as I am flaccid though still being visible. Sometimes they ache especially when I get an erection and touch them but the pain subsides when flaccid. They are sometimes very hard almost like they are calcified when erect. My physician said this was scar tissue and could be removed with surgery. I have no bend. Is it possible to see the plaques that are present in Peyronie's disease? Could this be Peyronie's disease?
• When I take Viagra I notice that it gives me a full erection and improves my "weak" erection from my Peyronie's disease. I only took it a couple of times and then heard not to take Viagra and stopped. It seems to help my erection and makes sex possible for me. Can Viagra make the disease worse or do damage?
• Will I obtain benefits if I rub collagenase instead of hydrocortisone on the place I feel the damage?
• Will the combination of Dupuytren's contracture and Peyronie's disease make a cure or improvement less likely?
Show all articles ( 58 ) Collapse Articles

• Changes in penis appearance

  • I am 25 years old, i have noticed my flaccid bend and have noticed hard plaques mainly on sides but sometimes the whole shaft seems hard when flaccid, my penis had gone a yellow colour and i am finding it very difficult to get erections when i do they are not ridgid, my flaccid keeps going really small an thin then it is large like rubber. My whole penis feels like rubber even when erect, i seem to be losing size will i get it back considering i am only 25
  • I first noticed my symptoms only about 3 months ago (painful erections, hard nodule under the skin when flaccid) and am currently in the "active" phase of the disease. Is there anything I should or should not be doing during this phase in order to minimize the eventual resulting curvature? It's only slightly noticeable (approx. 5-10%) and I'd like it to stay that way.
  • I have a slight curvature upward, a slight indentation in the middle of my shaft, and a small hard spot at the base. The hard spot and the pain started in the middle of the shaft, but have moved progressively to the base. Is this common?
  • I have had Peyronie's disease for 7 years and have recently noticed my penis shrinking in the flaccid state and becoming hard all over. When I get an erection my penis is bent 45 degrees to the right and when semi-erect it won't get fully hard. Is the scar preventing the corpus cavernosum from expanding or is the corpus cavernosum actually turning into fibrous tissue as well? What is the cause of this shrinkage effect?
  • I have just recently had an ultrasound scan and was told I have 7 plaques I have been told I have Peyronie's is this common to have 7 lumps as I don't know what to expect
  • I recently developed some curving in my penis. The penis is slightly curved even when not erect or aroused. Also there is some difficulty in urination. How likely is it that this is PD? Also should I completely stop masturbation?
  • I suffered a penile injury six years ago and was diagnosed with Peyronie’s but since then have been told that I am healed. I continue to see a deformity on and off. Is this permanent or will this too eventually go away.
  • I suffered a penile injury six years ago and was diagnosed with peyronies but since then have been told that I am healed. I continue to see a deformity on and off. Is this permanent or will this too eventually go away.
  • My bend is about 35% down and slightly to the right. Though I have never felt a plaque of any kind, there is a small indent in the right side close to the base. I do not experience pain unless I undergo more than one erection in a short amount of time. In the past few years, I have noticed a definite decrease in size, strength, stamina and intensity of climax. My urine flow has decreased and my penis in the flaccid state is both smaller and more limp than it ever has been. I can achieve erections, but for a short period of time and with little to no build up to a less than satisfying orgasm. These problems seem to be worsening. I am 27 and do not want the condition to worsen. Does this sound like a specific condition or symptom of PD and if so, what can I do?
  • Since I presented with PD about 6 years ago, I have observed a profound change in the appearance of my flaccid penis. What use to hang several inches outside of my body has shriveled up and retracted, and now resides close to my pubic hair. In addition, many of the veins and capillaries that once were plainly visible on my erect penis seem to have disappeared; some of those capillaries or small veins were very painful prior to their apparent demise. My flaccid penis often feels colder than it once did. Are all of these symptoms consistent with PD, or could other medical pathology be responsible for these changes? If so, what might they be?
  Show all articles ( 5 ) Collapse Articles

• General

  • A read a piece saying that daily erections are crucial for oxygenation and to prevent collagen from occurring? Is lack of daytime erections (none at all) a problem? If so, what can I do about it?
  • After a physical exam including a chemically induced erection, I've been told by my urologist that the next step is a Corpora cavernosagram to determine the cause of my peyronies. Is this a common procedure in diagnosing peyronies? Can sonography be used instead?
  • Although we are careful, my wife is experiencing difficulty with yeast infections. My PD curvature is about 90 degrees. Is PD the cause of this?
  • Are there any foods or drinks (coffee, tea, alcohol) that PD sufferers should eliminate? Are there any food or drinks known to help the condition?
  • As a spouse of a PD patient, what is the best way to approach the "inadequate" mental state my husband experiences — ignore, encourage, be candid, recommend medical treatment?
  • Can a condom that is too tight, which was left on while asleep cause an hourglass deformity? Could this hourglass shape be the beginning of PD?
  • Can PD explain why I have always had very little sensations in the skin of the penis? I have been going to different doctors for years about it, and now a urologist told me it might be related to PD. Is this a known phenomenon?
  • Can Peyronie's cause high elevated level of CPK?
  • Can Peyronie's disease occur a year after injury to the penis?
  • Can treatment options like injections of verapamil be just as effective if you wait too long for that treatment and the curvature is around 90 degrees?
  • Can you give us your professional opinion on the possibility of a cure anytime in the foreseeable future?
  • Does penile cancer also produce the plaque like growths in the penis shaft like Peyronie's disease?
  • How long is the inflammatory period of Peyronie's before a hard plaque can be detected?
  • I am 22. When I see my erect penis, it is curved to the left (slight curve). I feel no pain or lumps during masturbation. Should I seek treatment?
  • I am 23 years old, and I think I have Peyronie's. I have a significant bend and three inflamed soft scars on the right on the side of my shaft. The bend is about 45 degrees to the left and very apparent upon erection. However, I do not have any pain when I get an erection and the lumps are soft, not hard. I have been pretty stable with the condition for three years, but I am trying to find an alternative way to treat this. I have taken Potaba with no success. I am currently on vitamin E and I am noticing no difference. I read up on the serrapetase, nattokinase and bromelain for dissolving scar tissue. Is there anything I can do to help this condition?
  • I am 23 years-old. I don't get excited or develop an erection until I watch a porn movie. I have a slight bending towards the right and I feel that my erections are not hard and occur infrequently. Do I suffer from Peyronie's disease, and is it recoverable?
  • I am 25 years old, I have noticed my flaccid bend and have noticed hard plaques mainly on sides but sometimes the whole shaft seems hard when flaccid, my penis had gone a yellow color and I am finding it very difficult to get erections. When I do they are not rigid, my flaccid keeps going really small and thin then it is largely like rubber. My whole penis feels like rubber even when erect, I seem to be losing size will I get it back considering I am only 25.
  • I am 38 and have a 30-degree ventral and 45-degree left curvature with moderate to severe pain and discomfort. I do not recall a time when I did not have this curvature and therefore believe I have a congenital curvature rather than Peyronie's disease. It appears that men with congenital curvature rarely experience pain. Is it normal to have pain with congenital curvature, and is it possible and/or likely to have Peyronie's disease and congenital curvature?
  • I am 50 years old and recently diagnosed with Peyronie's. I've been to 2 urologists, tried Potaba (stopped; too many side effects) and using verapamil gel at night. Surgery was also recommended. I've done some research and have seen the Extender. Does this work? I'm getting mixed reviews. I have a 30-40% downward curve.
  • I am a 45 year old man. I have had Peyronie's disease for about a year and a half. It bothers me more than I can express. The glans is smaller now and it is embarrassing in daylight. I know it must sound trivial, given the true horrors in the world, but making love is one of the things I was really good at. Can you help me?
  • I appear to have an unusual form of PD. I was diagnosed by my Urologist as having PD at the base of the penis near the scrotum. I do not have deformity or bend, but I do have a soft end to the penis. Why is this occurring?
  • I do not know if I should see an urologist. I have erection problems. I still get nighttime and morning erections. However, I have trouble during intercourse. My erection points straight down. If I pull it to stand up, there is tension.
  • I experience premature ejaculation and in addition, when I urinate it flows out in different directions. Could PD be the cause of both of these effects?
  • I had surgery (temporalis fascia graft) last summer. My penis is approx 3 inches in length. Before Peyronie's it was 7 inches. I still have the curve and use the Fastrack traction and soma pump. Using both has improved the use of the traction device because it enlarges the gland tor the device to hold onto the penis. However, after a month of using it about 2 hours a day, I have noticed that the plague seems softer but my penis still has a bend and continues to be short. Will this improve with consistent use?
  • I have an extreme case of PD, upward and back. I have used treatments ranging from Potaba to verapamil alone or with DMSO topically. Any advice you can give for this extreme case of PD and any other steps to consider?
  • I have been experiencing Peyronie's disease for the last 6 months or so. Currently, the bend is about 30 degrees. The scar is on the right of upper part of penis, leading to curvature towards right side. Continuous pain is associated even when it is flaccid. When erected, it remains the same and becomes more precise at the point of scar. When once in a blue moon the pain is not present, I feel sexual desire. Otherwise it is not that much intense. Moreover it has been superimposed by severe depression. Would you suggest something to get around it? Especially pain associated with it as it has made my life miserable.
  • I have detected hard rings on my penis which are felt only during an erection. Peyronie's disease has not been diagnosed. Can I stop any further deterioration since finding this early? What signs should I look for if this is indeed PD?
  • I have had PD for 10 months, with onset of curvature for 1 month and painful erections for 2 months. The curvature is 45 degrees dorsally and only at the end of the penis. The erections are strong, except for the distal third which is somewhat compromised. I am wondering whether my progression time line is faster than what I have read. I am 55 and I am worried that my condition will get worse or will it stabilize as it currently exists.
  • I have heard a lot about Peyronie's disease, but nowhere did it mention if this is a temporary or permanent condition. Is it possible for the body to dissolve the tissue that causes the curvature?
  • I have PD and fortunately do not have difficulty with erection. I have heard about taking erectile dysfunction drugs like Viagra to promote "penile health." Does this help?
  • I was diagnosed in 2000 with PD. My original doctor suggested I let time pass and see what happens. Luckily, I listened to others and went to a specialist. I was treated with medicine for a year and the pain eventually went away. About 3 weeks ago, I began noticing a burning pain, but it had come from time to time as I healed, but I have no other problems. My question is, can the pain that I am feeling now be the result of some remaining scar tissue loosening, or am I headed for another bout of PD?
  • I'm 56 and was diagnosed with PD 9 years ago. I am diabetic, and was also diagnosed with Dupuytren's contracture. In the last few years, my erections have really shrunk. I used to have about a 6-inch erection now my erections are about the size of my thumb (both in length and thickness). My wife and I haven't had sex in about 6 years and I can't even discuss this with her. Over the last 13 months I have added Plavix, Toprol XL, and Zocor to the insulin I take. Is there anything that can help me or is there something else coming along in the next year or two?
  • I've had Peyronie's disease for about 6 years. I can still get adequate erections and achieve intromission. However, there appears to be loss of sensation on one side of the penis which makes it difficult to reach orgasm, causing frustration for me and my partner. Could this be treated and/or reversed?
  • In young men, once PD enters the chronic phase, can it convert back to the acute phase resulting in new plaque?
  • In your opinion, what is the best treatment to prevent fibrosis from spreading around the tunica or into the vascular tissue for a Peyronie's disease patient?
  • Is it possible for PD sufferers to have flare-ups in pain at the plaque site (even when the penis is flaccid) for 10 to 20 years?
  • Is it possible to get stretch marks on the outer skin of the penis? I have developed two horizontal red "stripes" that resemble stretch marks. Is this Peyronie's disease? What can I do to alleviate the problem? I am terrified that this will result in Peyronie's disease.
  • Is there any data from the pilot study performed by Dr. Levine on traction therapy with respect to patient's response tracked during the 6-month study?
  • Is there any way of determining exactly how long one has had PD?
  • My erections seem shorter than normal; the penis seems more slender and the head of the penis never gets hard or firm. I assumed I had Peyronie's disease, but the doctor said there was no hard spot which apparently is typical. I am wondering if there could be another cause such as low testosterone.
  • My penis does not have a curvature. However, are these symptoms associated with PD — numbness and white spots on the tip of the glans and occasional numbness of the testicles. My erections are also not as stiff.
  • What is the best and the most accurate test to evaluate any scarring or scar tissue in the tunica to determine whether it is considered PD? Do you recommend chronic use of small doses of Viagra as an anti-fibrotic regimen? What do you think about using Trental in conjunction with nightly use of Viagra?
  • When a man with Peyronie's disease also has impotence what can be done?
  • When I am erect only the head of my penis tilts to the right while the shaft remains straight. Is this PD?
  • When I get an erection, on the left side of my penis there are 2 very visible band or lumps that are palpable, less than 3 cm, that appear to be in the erectile tissue, that span across the left side of the shaft which become bigger and harder when I get an erection and smaller as I am flaccid though still being visible. Sometimes they ache especially when I get an erection and touch them but the pain subsides when flaccid. They are sometimes very hard almost like they are calcified when erect. My physician said this was scar tissue and could be removed with surgery. I have no bend. Is it possible to see the plaques that are present in Peyronie's disease? Could this be Peyronie's disease?
  • Will I obtain benefits if I rub collagenase instead of hydrocortisone on the place I feel the damage?
  • Will the combination of Dupuytren's contracture and Peyronie's disease make a cure or improvement less likely?
  Show all articles ( 42 ) Collapse Articles

• Pain

  • Along with the indentation, and the lump when I am flaccid, I also have trouble maintaining fuller erections, and I have noticed pain at times even when flaccid. Is it safe to try and maintain erections, masturbate and/or have sex?
  • I am 36 years old, I am able to get an erection, but it does not appear to have the same shape when I am lying on back, and when I try to correct this, it hurts. What can I do?
  • I was diagnosed with PD about 2.5 years ago. Today the pain is gone, and I have sex although my penis is never as hard as it was before. I was wondering what were the chances, if any, of the PD recurring?
  • I'm 65, have had minor PD symptoms in the way of excessive swelling during erection & slight pain and slight curvature of the tip of the penis beginning about 6 months ago with no injury as the cause. My urologist detected a slight mass at the base of my penis on the top side. I have a history of keloid scarring from two surgeries and successfully reduced scarring to minimum by repetitive, aggressive massaging of the scars. Might this work with PD?
  • My husband has had Peyronie's disease for 16 months now. Will the pain during ejaculation ever go away?

• Viagra

  • When I take Viagra I notice that it gives me a full erection and improves my "weak" erection from my Peyronie's disease. I only took it a couple of times and then heard not to take Viagra and stopped. It seems to help my erection and makes sex possible for me. Can Viagra make the disease worse or do damage?

Surgery

• Are most patients who go through the Nesbit procedure or the grafting procedure better off after the surgery than before?
• Are there any surgeries for curvature that correct the shape of the penis in the flaccid as well as the erect state?
• Are there any US urologists who use lithotripsy for treatment?
• As a spouse of a PD patient, what is the best way to approach the "inadequate" mental state my husband experiences — ignore, encourage, be candid, recommend medical treatment?
• Can the laser knife treatment for cancerous tumors be used to treat Peyronie's disease instead of invasive surgery?
• Do you know the basic cost of the more common treatments for PD such as Nesbit plication, grafting, etc? Do most insurances cover any of these costs?
• Does the Lue procedure in conjunction with plaque incision give good results?
• Have you heard of the procedure used where Bovine pericardium graft is employed for resolving curvature?
• How much would be the loss of length after the surgery?
• I had surgery for Peyronies disease in April of 2012. I have an allergy to iodine but the incompetent post-op nurse put iodine all over my penis to insert a catheter. This caused massive quarter-sized blisters all over the head of my penis that spread into the sutures. I keep having electrical shooting pains through my penis frequently. The surgical doctor said I have nerve damage from the allergic reaction. The hospital is arguing this point saying this is not possible. Any thoughts?
• I have a 90-degree bend, and have for 3 years. Is plaque incision and patch grafting a viable operation and what are the chances of success?
• I have a bend that goes straight down and slightly to the left. Would surgery help this type of Peyronie's?
• I have been diagnosed with PD for over a year. I am interested in getting the surgical procedure that removes the plaque and replaces it with a graft made from pig intestine. Can this procedure preserve length and girth? What is your opinion of this procedure?
• I have had Peyronie's disease for about 5 years, my curvature is about 60 degrees, and intercourse is still possible. I have tried everything and am considering surgery. What is recommended in this type of case?
• I have had Peyronie's for about 2 year now; I have tried verapamil cream, no change. My doctor is so negative regarding surgery. Before the disease when erect I was 8 inches, now I am about four and then a two inch bend at a 90- degree angle up and have also lost some circumference. I have no pain at all. I read an article about a new procedure where they sort of scrape the scar with a needle length wise.
• I have Peyronie's disease and recently have gone through implant surgery. However, the length and girth of my penis was significantly decreased and my wife no longer gains any feeling/satisfaction because of the reduction in girth. Is there anything that can be done to increase the girth such as penile widening by injecting my own fat cells into the penis?
• I recently had surgery for a congenitally curved penis. The surgery was called a "penile plication." I have no feeling in the last inch of the shaft and the head. Is this normal, and will the feeling return when I am further healed?
• I’m 21 and I'm going to have surgery of penile plication. How often does the patient have pain after this procedure? How long does the pain stay? Is the scar very uncomfortable? How much time to recuperate from this surgery?
• If the healing process is more efficient in younger men with PD, why are doctors reluctant to perform surgery on them?
• If the penis has a 70-degree bend upward and surgery is performed to correct this condition, what would be the expected result? (Worse and best case).
• In men who have severe curvature or hour glass deformity, will the grafting procedure cause a further loss of length or width? If so, do you recommend the vacuum pump after surgery and does it help with length or width?
• Is PD progressive? Will I continue to lose length and girth? Is there any type of laser surgery to reduce calcified scar tissue?
• Is transplantation for PD impossible?
• Last year my penis began to point downward and developed an indentation on the topside. My penis is now bent about 90 degrees and it is hinged. I can straighten it enough to pull it where it needs to go…no pain, ever. After seeing a urologist that prescribed Potaba, then researching about the various treatments, I found several additional options that may help, including colchicine, collagenase, and finally surgery. What is the best treatment or surgical option for this kind of PD?
• Regarding penile implants, do you predict technology will modernize these? Such as enabling the implant to be the same size inflated, as once the original erection was, or maybe larger?
• What are the average fees associated with the Nesbit surgery from American urologists? Do you know if this surgery is performed in Canada?
• What is the average recovery time and success of the graft procedure when using graft material from a hydrocele from the testicle?
• What is the best surgical procedure for a downward 60-90 degree congenital penis curvature?
• What is the effectiveness of incision/excision surgery where a graft will fill in the area worked on?
Show all articles ( 24 ) Collapse Articles

• General

  • Are there any surgeries for curvature that correct the shape of the penis in the flaccid as well as the erect state?
  • Are there any US urologists who use lithotripsy for treatment?
  • Can the laser knife treatment for cancerous tumors be used to treat Peyronie's disease instead of invasive surgery?
  • Do you know the basic cost of the more common treatments for PD such as Nesbit plication, grafting, etc? Do most insurances cover any of these costs?
  • Does the Lue procedure in conjunction with plaque incision give good results?
  • How much would be the loss of length after the surgery?
  • I had surgery for Peyronies disease in April of 2012. I have an allergy to iodine but the incompetent post-op nurse put iodine all over my penis to insert a catheter. This caused massive quarter-sized blisters all over the head of my penis that spread into the sutures. I keep having electrical shooting pains through my penis frequently. The surgical doctor said I have nerve damage from the allergic reaction. The hospital is arguing this point saying this is not possible. Any thoughts?
  • I have a 90-degree bend, and have for 3 years. Is plaque incision and patch grafting a viable operation and what are the chances of success?
  • I have a bend that goes straight down and slightly to the left. Would surgery help this type of Peyronie's?
  • I have been diagnosed with PD for over a year. I am interested in getting the surgical procedure that removes the plaque and replaces it with a graft made from pig intestine. Can this procedure preserve length and girth? What is your opinion of this procedure?
  • I have had Peyronie's disease for about 5 years, my curvature is about 60 degrees, and intercourse is still possible. I have tried everything and am considering surgery. What is recommended in this type of case?
  • I have Peyronie's disease and recently have gone through implant surgery. However, the length and girth of my penis was significantly decreased and my wife no longer gains any feeling/satisfaction because of the reduction in girth. Is there anything that can be done to increase the girth such as penile widening by injecting my own fat cells into the penis?
  • I recently had surgery for a congenitally curved penis. The surgery was called a "penile plication." I have no feeling in the last inch of the shaft and the head. Is this normal, and will the feeling return when I am further healed?
  • I’m 21 and I'm going to have surgery of penile plication. How often does the patient have pain after this procedure? How long does the pain stay? Is the scar very uncomfortable? How much time to recuperate from this surgery?
  • If the healing process is more efficient in younger men with PD, why are doctors reluctant to perform surgery on them?
  • If the penis has a 70-degree bend upward and surgery is performed to correct this condition, what would be the expected result? (Worse and best case).
  • In men who have severe curvature or hour glass deformity, will the grafting procedure cause a further loss of length or width? If so, do you recommend the vacuum pump after surgery and does it help with length or width?
  • Last year my penis began to point downward and developed an indentation on the topside. My penis is now bent about 90 degrees and it is hinged. I can straighten it enough to pull it where it needs to go…no pain, ever. After seeing a urologist that prescribed Potaba, then researching about the various treatments, I found several additional options that may help, including colchicine, collagenase, and finally surgery. What is the best treatment or surgical option for this kind of PD?
  • What are the average fees associated with the Nesbit surgery from American urologists? Do you know if this surgery is performed in Canada?
  • What is the best surgical procedure for a downward 60-90 degree congenital penis curvature?
  • What is the effectiveness of incision/excision surgery where a graft will fill in the area worked on?
  Show all articles ( 16 ) Collapse Articles

• Implants and Graphs

  • Are most patients who go through the Nesbit procedure or the grafting procedure better off after the surgery than before?
  • As a spouse of a PD patient, what is the best way to approach the "inadequate" mental state my husband experiences — ignore, encourage, be candid, recommend medical treatment?
  • Have you heard of the procedure used where Bovine pericardium graft is employed for resolving curvature?
  • Regarding penile implants, do you predict technology will modernize these? Such as enabling the implant to be the same size inflated, as once the original erection was, or maybe larger?
  • What is the average recovery time and success of the graft procedure when using graft material from a hydrocele from the testicle?

• New Procedures

  • I have had Peyronie's for about 2 year now; I have tried verapamil cream, no change. My doctor is so negative regarding surgery. Before the disease when erect I was 8 inches, now I am about four and then a two inch bend at a 90- degree angle up and have also lost some circumference. I have no pain at all. I read an article about a new procedure where they sort of scrape the scar with a needle length wise.
  • Is PD progressive? Will I continue to lose length and girth? Is there any type of laser surgery to reduce calcified scar tissue?

• Transplants

  • Is transplantation for PD impossible?