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- After a biking trauma I have erectile dysfunction and pain when sitting. Erections are rare without desire and my penis is curved and sticks to my body. I am 22, do I suffer from PD?
- Are you aware if a "flex sig" colon exam can bring about PD?
- Can hypertensions cause Peyronie's disease?
- Did my existing Dupuytren's contraction condition increase my possibility of PD because of the cystoscopy?
- Do you recommend discontinuing the use of tobacco products prior to installing an implant? Will the smoking constrict blood flow and create any additional dangers?
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Drugs (Cialis, Viagra, Rogaine, etc)
- Has any correlation been shown (or link) between the onset of Peyronie's and the use of any drugs, ie, Lipitor, Tricor, Rogaine?
- Is there any association of PD with use of ED drugs such as Cialis. Could taking Viagra and Cialis once or twice a month over 2 yrs have caused me to develop Peyronie's Disease?
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Dupuytren's Disease
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General
- Are you aware if a "flex sig" colon exam can bring about PD?
- Do you recommend discontinuing the use of tobacco products prior to installing an implant? Will the smoking constrict blood flow and create any additional dangers?
- Does PD cause sterilization?
- Has there been determined to be a link between PD and other pelvic disorders, such as prostatitis, interstitial cystitis, or epididymitis? Is it possible that such disorders could lead to Peyronie's or that one could lead to a false diagnosis of the other?
- I am a 19 year old man. I have not had sex yet but I notice a bend of 25 degrees towards the left and 30 degrees upwards when fully erect. There are no scars or lumps detected. Can PD affect younger men? Are these bends permanent?
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Hypertension/Stress
- Can hypertensions cause Peyronie's disease?
- In any of the cases you've seen, is stress indicated as a possible trigger for Peyronie's? I ask, because in me its appearance coincided with a very stressful period of my life.
- What are the implications of PD secondary to catheterization trauma as regards the causal factors of PD? Why would inflammation in the urethra lead to PD? Why would injury to a separated part of the penis find its way to the tunica?
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Trauma
- After a biking trauma I have erectile dysfunction and pain when sitting. Erections are rare without desire and my penis is curved and sticks to my body. I am 22, do I suffer from PD?
- I had a piercing in my penis (a PA) a couple of years ago. When I had it stretched to 5 mm, it appears the "lump" in my penis and the bend occurred. Have you heard of this before? Is it coincidental?
- I have been riding a bicycle for 60+ years, and continue to ride daily. I often have penile numbness after a period of time in the saddle. Could this be a cause of PD, and cause further exacerbation of my PD? Do you have any recommendations on bicycle saddles, or bicycle types, that would hep reduce penile numbness/trauma? Thank you.
- I was kicked in the penis six weeks ago. I was diagnosed with Peyronie's disease this week. I have not had intercourse in a year or more. Could the injury have caused the Peyronie's disease?
- Since trauma and micro-trauma are widely accepted as a major cause of PD, what is believed to be the level of risk from intralesional verapamil (ILV) treatments? Also, does the aging process make the tunica more subject to damage from ILV treatments?
- Can we generate our own new organ from DNA or stem cell therapy?
- Could you give your opinion regarding stem cell research as a solution? Are there any studies being done anywhere in the world with stem cell and Peyronie's?
- Do you have any current information on the use of stem cell therapy in treating PD?
- Given the advances in reconstructive surgery especially in light of the near full face transplant recently performed, what is the progress being made with respect to plaque excision and implantation of regenerated tunica albuginea for correction of Peyronie's disease?
- Will regeneration and transplantation of part or the entire penis occur in the near future?
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Stem Cell Research
- Can we generate our own new organ from DNA or stem cell therapy?
- Could you give your opinion regarding stem cell research as a solution? Are there any studies being done anywhere in the world with stem cell and Peyronie's?
- Do you have any current information on the use of stem cell therapy in treating PD?
- Given the advances in reconstructive surgery especially in light of the near full face transplant recently performed, what is the progress being made with respect to plaque excision and implantation of regenerated tunica albuginea for correction of Peyronie's disease?
- Will regeneration and transplantation of part or the entire penis occur in the near future?
- A naturopathic doctor also recommends L-arginine for PD, but insists that a low dose will do nothing. No, he is not selling L-arginine. He recommends a very high dose — at least 3 grams per day and working up to 21 grams per day. Do you know of any risks to trying this?
- Are interferon injections as effective as verapamil injections?
- Are there any contraindications to using Adderall when one has a diagnosis of PD or if one were taking Trental and L-arginine as well as 10 mg of Cialis every other night?
- Besides a urologist manually checking the penis for scarring or nodules for possible Peyronie's disease, what other procedures (such as ultrasound) are more valid at determining if one does in fact have this disease? How accurate is checking for this disease manually?
- By reducing the plaque formations associated with Peyronie's disease is it possible to restore the elasticity of the penis or will the tissue remain in the non-elastic state due to the scarring?
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Extracorporeal shock wave therapy (ES)
- Besides a urologist manually checking the penis for scarring or nodules for possible Peyronie's disease, what other procedures (such as ultrasound) are more valid at determining if one does in fact have this disease? How accurate is checking for this disease manually?
- I am a sixty-four year old white male living in the United Kingdom, six foot tall, twelve and a half stone in weight and I consider myself to be in good health. I am not on any medication; I exercise regularly, sleep well, eat healthily and had a good sex-life with my partner. At the end of March 2013 I was diagnosed with Peyronie's Disease. I have been offered a course of ESWT (Extracorporeal shock wave therapy). My question: This procedure ESWT, how effective is it in treating Peyronie's Disease, is it too early to do this procedure as it is only been six/seven months since the disease first started and how safe is the ESWT procedure? Many thanks for all the information the association has published, it has helped me enormously to come to terms with the disease.
- I am in physical therapy and want to do ultrasound for treatment of Peyronie's. What is the protocol, I have forgotten since school how many w/cm2 and what intensity to use. Also, do you use pulse or continuous ultrasound?
- I have been considering ESWT treatment for Peyronie's disease but I would like to know about the percentage of successful treatment. I don't have a lot of pain with the erection but I have the curvature? I also take Viagra because of inadequate blood flow. Does the ESWT increase blood flow or does it just correct the curvature?
- Is it possible for iontophoresis to soften or even change any calcification that may be present in the plaque?
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General
- A naturopathic doctor also recommends L-arginine for PD, but insists that a low dose will do nothing. No, he is not selling L-arginine. He recommends a very high dose — at least 3 grams per day and working up to 21 grams per day. Do you know of any risks to trying this?
- By reducing the plaque formations associated with Peyronie's disease is it possible to restore the elasticity of the penis or will the tissue remain in the non-elastic state due to the scarring?
- Do penile enlargement pills and patches work?
- Hand surgeons for Dupuytren's contractures have been successfully using an open percutaneous needle fasciotomy procedure instead of an open procedure. Why can't this closed percutaneous technique be a procedure used by urologists for Peyronie's patients?
- How do patients who have curvatures of the penis greater than 30 degrees do when the curvature involves just the distal end of the penis? Can it correct itself without treatment? What about vitamin E? Do we typically see worsening of the disease after a period of 12-18 months?
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Injections
- Are interferon injections as effective as verapamil injections?
- Can Botox work at relaxing and softening the plaque?
- Do you know of any doctors who give collagenase injections for Peyronie's disease?
- I have had Peyronie's disease for 1 year and 10 months and just went through Intron A injections every 2 weeks for 3 months. I have not seen any change. The Peyronie's specialist wants to do a second wave of injections. If this did not work at all, do you think it is wise to go through a second injection battery?
- I have read that cortisone injections have been effective in some cases, is this so?
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Medication
- Are there any contraindications to using Adderall when one has a diagnosis of PD or if one were taking Trental and L-arginine as well as 10 mg of Cialis every other night?
- Can pentoxifylline help with increasing blood flow when a man has PD? Also is Niacin also an alternative that might achieve any results?
- Can you give some more data about fexofenadine in PD treatment?
- Do lasers help with deformity at all?
- I developed a sudden onset of Peyronie's disease following treatment of blood pressure with Prinivil. This resulted in curvature to the left, as well as a 2-inch loss of length. If I were able to get my blood pressure down off of this medications would this help?
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Nutraceuticals
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Traction devices
- Articles coming soon
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Tropical Treatment
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Vacuum pumps
- Can vacuum therapy cause damage?
- Do penis stretchers actually help with Peyronie's disease?
- Does the use of vacuum therapy help eliminate the scarring which occurs from Peyronie's disease?
- Have vacuum appliances had any effect on helping Peyronie's patients? Since there seems to be quite a controversy about the use of vacuum erection devices for PD therapy, would the doctor(s) provide any up to date information about the proper uses for the VEDs. Especially using the VEDs for PD.
- I have seen literature describing the use of penis traction devices, such as the Pro-Extender, to treat Peyronie's. Unlike vacuum devices, these traction devices are used for 8-12 hours a day. What is your opinion on this approach?
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Vitamins/Herbal Supplements
- Do you have any comment on the study of taking Co-Q10 to help Peyronie's?
- How long should I take the vitamin E?
- I have been diagnosed with PD by a urologist 3 months ago. I am 59. He has prescribed 800 IU of vitamin E daily & also Infam-away (a hi-potency enzyme formula) capsules 6 daily on a empty stomach. Nothing has helped after taking these medicines for 3 months. Erections are very painful and curvature has developed to the left. An indentation about 1 inch below the glans has also developed. He has basically told me that there is nothing else he can do. My primary care physician admits that this is a disease that not much is known as to the whys and what will work to help the pain and hopefully stop or reverse the curvature which at present is 30-40%. I was given a pain killer to help especially if erections get too painful. Are there any over-the-counter or on the internet medicines that may help?
- I have been using transdermal verapamil 15% by www.pdlabs.net for the last 5 months with no visible results. They told me that the cream would remodel the plaque into healthy tissue and while they couldn't use the word cure they assured me their patented delivery system resulted in proper absorption of the medicine while other compounds were ineffective. They claimed this was one of the main reasons for so much misinformation about it. What do you make of their claims?
- I have severe deformation from PD, do you think I should try topical Verapamil?
- I am 23 years old and having treatment of Peyronie’s disease applying verapamil gel as prescribed by doctor since 4 months. I still masturbate almost twice a week. Will this make my condition worse?
- I live in Romania: My penis has a downward bend, something like a banana. I don't feel any scar tissue, and I don't have erection problems. I am 19 and I have a girlfriend, but we haven't been able to have sex. Could this be Peyronie's disease?
- Is it common for a Peyronie's patient to have no sex drive, become depressed and impotent?
- Is it necessary that the full part of the penis be inserted into the vagina?
- My boyfriend, age 52, cannot reach orgasm during intercourse and both of us work very hard to achieve this. It usually takes about 30 minutes of masturbation after sex and oral sex. His penis is somewhat cobra shaped and just a little bent. Frequently during intercourse or oral sex he will lose his erection. What could be causing this?
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General
- I am 23 years old and having treatment of Peyronie’s disease applying verapamil gel as prescribed by doctor since 4 months. I still masturbate almost twice a week. Will this make my condition worse?
- Is it necessary that the full part of the penis be inserted into the vagina?
- My penis has a curvature towards the right when erect. It has a deviation at the base, as well. There is no pain when erect or flaccid. I had sexual intercourse, but only a part of my penis got inserted. Is this a problem?
- My penis is always bent to the left; it is almost a 35-degree curve, 1 inch from the base of the penis. Is it Peyronie's or something else? Will I be able to have intercourse properly or is it a severe problem? Are you aware of any physician in Pakistan (Lahore), who is experienced with Peyronie's disease?
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Sex
- I live in Romania: My penis has a downward bend, something like a banana. I don't feel any scar tissue, and I don't have erection problems. I am 19 and I have a girlfriend, but we haven't been able to have sex. Could this be Peyronie's disease?
- My boyfriend, age 52, cannot reach orgasm during intercourse and both of us work very hard to achieve this. It usually takes about 30 minutes of masturbation after sex and oral sex. His penis is somewhat cobra shaped and just a little bent. Frequently during intercourse or oral sex he will lose his erection. What could be causing this?
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Sex Drive
- A read a piece saying that daily erections are crucial for oxygenation and to prevent collagen from occurring? Is lack of daytime erections (none at all) a problem? If so, what can I do about it?
- After a physical exam including a chemically induced erection, I've been told by my urologist that the next step is a Corpora cavernosagram to determine the cause of my peyronies. Is this a common procedure in diagnosing peyronies? Can sonography be used instead?
- Along with the indentation, and the lump when I am flaccid, I also have trouble maintaining fuller erections, and I have noticed pain at times even when flaccid. Is it safe to try and maintain erections, masturbate and/or have sex?
- Although we are careful, my wife is experiencing difficulty with yeast infections. My PD curvature is about 90 degrees. Is PD the cause of this?
- Are there any foods or drinks (coffee, tea, alcohol) that PD sufferers should eliminate? Are there any food or drinks known to help the condition?
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Changes in penis appearance
- I am 25 years old, i have noticed my flaccid bend and have noticed hard plaques mainly on sides but sometimes the whole shaft seems hard when flaccid, my penis had gone a yellow colour and i am finding it very difficult to get erections when i do they are not ridgid, my flaccid keeps going really small an thin then it is large like rubber. My whole penis feels like rubber even when erect, i seem to be losing size will i get it back considering i am only 25
- I first noticed my symptoms only about 3 months ago (painful erections, hard nodule under the skin when flaccid) and am currently in the "active" phase of the disease. Is there anything I should or should not be doing during this phase in order to minimize the eventual resulting curvature? It's only slightly noticeable (approx. 5-10%) and I'd like it to stay that way.
- I have a slight curvature upward, a slight indentation in the middle of my shaft, and a small hard spot at the base. The hard spot and the pain started in the middle of the shaft, but have moved progressively to the base. Is this common?
- I have had Peyronie's disease for 7 years and have recently noticed my penis shrinking in the flaccid state and becoming hard all over. When I get an erection my penis is bent 45 degrees to the right and when semi-erect it won't get fully hard. Is the scar preventing the corpus cavernosum from expanding or is the corpus cavernosum actually turning into fibrous tissue as well? What is the cause of this shrinkage effect?
- I have just recently had an ultrasound scan and was told I have 7 plaques I have been told I have Peyronie's is this common to have 7 lumps as I don't know what to expect
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General
- A read a piece saying that daily erections are crucial for oxygenation and to prevent collagen from occurring? Is lack of daytime erections (none at all) a problem? If so, what can I do about it?
- After a physical exam including a chemically induced erection, I've been told by my urologist that the next step is a Corpora cavernosagram to determine the cause of my peyronies. Is this a common procedure in diagnosing peyronies? Can sonography be used instead?
- Although we are careful, my wife is experiencing difficulty with yeast infections. My PD curvature is about 90 degrees. Is PD the cause of this?
- Are there any foods or drinks (coffee, tea, alcohol) that PD sufferers should eliminate? Are there any food or drinks known to help the condition?
- As a spouse of a PD patient, what is the best way to approach the "inadequate" mental state my husband experiences — ignore, encourage, be candid, recommend medical treatment?
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Pain
- Along with the indentation, and the lump when I am flaccid, I also have trouble maintaining fuller erections, and I have noticed pain at times even when flaccid. Is it safe to try and maintain erections, masturbate and/or have sex?
- I am 36 years old, I am able to get an erection, but it does not appear to have the same shape when I am lying on back, and when I try to correct this, it hurts. What can I do?
- I was diagnosed with PD about 2.5 years ago. Today the pain is gone, and I have sex although my penis is never as hard as it was before. I was wondering what were the chances, if any, of the PD recurring?
- I'm 65, have had minor PD symptoms in the way of excessive swelling during erection & slight pain and slight curvature of the tip of the penis beginning about 6 months ago with no injury as the cause. My urologist detected a slight mass at the base of my penis on the top side. I have a history of keloid scarring from two surgeries and successfully reduced scarring to minimum by repetitive, aggressive massaging of the scars. Might this work with PD?
- My husband has had Peyronie's disease for 16 months now. Will the pain during ejaculation ever go away?
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Viagra
- Are most patients who go through the Nesbit procedure or the grafting procedure better off after the surgery than before?
- Are there any surgeries for curvature that correct the shape of the penis in the flaccid as well as the erect state?
- Are there any US urologists who use lithotripsy for treatment?
- As a spouse of a PD patient, what is the best way to approach the "inadequate" mental state my husband experiences — ignore, encourage, be candid, recommend medical treatment?
- Can the laser knife treatment for cancerous tumors be used to treat Peyronie's disease instead of invasive surgery?
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General
- Are there any surgeries for curvature that correct the shape of the penis in the flaccid as well as the erect state?
- Are there any US urologists who use lithotripsy for treatment?
- Can the laser knife treatment for cancerous tumors be used to treat Peyronie's disease instead of invasive surgery?
- Do you know the basic cost of the more common treatments for PD such as Nesbit plication, grafting, etc? Do most insurances cover any of these costs?
- Does the Lue procedure in conjunction with plaque incision give good results?
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Implants and Graphs
- Are most patients who go through the Nesbit procedure or the grafting procedure better off after the surgery than before?
- As a spouse of a PD patient, what is the best way to approach the "inadequate" mental state my husband experiences — ignore, encourage, be candid, recommend medical treatment?
- Have you heard of the procedure used where Bovine pericardium graft is employed for resolving curvature?
- Regarding penile implants, do you predict technology will modernize these? Such as enabling the implant to be the same size inflated, as once the original erection was, or maybe larger?
- What is the average recovery time and success of the graft procedure when using graft material from a hydrocele from the testicle?
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New Procedures
- I have had Peyronie's for about 2 year now; I have tried verapamil cream, no change. My doctor is so negative regarding surgery. Before the disease when erect I was 8 inches, now I am about four and then a two inch bend at a 90- degree angle up and have also lost some circumference. I have no pain at all. I read an article about a new procedure where they sort of scrape the scar with a needle length wise.
- Is PD progressive? Will I continue to lose length and girth? Is there any type of laser surgery to reduce calcified scar tissue?
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Transplants