Causes

It is extremely unlikely that TURP is associated with PD. Given the number of TURPs that have been performed at least historically, we should have seen a signal of a link. Furthermore, in my patients who link the two together than man has a dorsal plaque which

Peyronie’s disease is a disorder of wound healing which often times will present with pain because of inflammation associated with the initial scarring process. The inflammation irritates the pain fibers which are typically activated when the penis becomes erect causing stretching of these nerve fibers. When the

Peyronie’s disease is a disorder of wound healing which often times will present with pain because of inflammation associated with the initial scarring process. The inflammation irritates the pain fibers which are typically activated when the penis becomes erect causing stretching of these nerve fibers. When the

A flexible sigmoidoscopy is performed for evaluation of the rectum and lower sigmoid colon. This procedure, to my knowledge, has not been associated with triggering Peyronie’s disease as there is no direct trauma to the penis or the genitalia. Certainly, it is possible that any trauma in

This is an interesting question as the chronic pelvic pain disorders such as prostatitis and interstitial cystitis and possibly chronic orchialgia (testicular pain) appear to be linked to the concept of chronic pain where there is a central nervous system modification of nerve response. These are pain

Absolutely, tobacco use around the time of surgery will increase the risk of complications and may impede proper healing because of reduced blood flow. Tobacco intake in any form will cause blood vessels to constrict after acute use, but with chronic exposure tobacco will accelerate the aging

Several studies have shown that 10% of the men presenting with PD are under 40 years old. Younger men with PD have also been shown to do well with non-surgical treatment presumably because the healing response is better in younger men. However, most men under 20 who

There is no connection between sterilization and PD. If the deformity is so bad that it prevents vaginal penetration, conception will be compromised, but this does not make the man sterile.

Dr. Levine answers: It is unlikely that any type of urethral manipulation would trigger Peyronie’s disease unless it resulted in a downward or ventral bend of the penis. This would suggest that urethral trauma may have activated some inflammation and scarring on the undersurface of the penis

Dr. Levine answers: At this point there is no evidence of direct association with the use of any medication and Peyronie’s disease. Historically, articles suggested in association with various medications, but these were typically case reports and due to a lack of understanding of the disease process.