I am 65 and was diagnosed with PD 18 months ago. I have a 50-degree upward curvature and some associated erectile dysfunction, but with Viagra I am still able to be sexually active. I plan to purchase the Fastsize Extender and use it in conjunction with L-arginine in hopes of reducing the degree of curvature. Is there a problem using L-argenine and Viagra together?

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  • I am 65 and was diagnosed with PD 18 months ago. I have a 50-degree upward curvature and some associated erectile dysfunction, but with Viagra I am still able to be sexually active. I plan to purchase the Fastsize Extender and use it in conjunction with L-arginine in hopes of reducing the degree of curvature. Is there a problem using L-argenine and Viagra together?
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Dr. Levine answers: As you know, erectile dysfunction (ED) frequently accompanies Peyronie’s disease and in fact up to 90% of patients have been reported some reduction of rigidity. The use of all three of the PDE-5 inhibitors (i.e. Viagra, Levitra, and Cialis) have been used successfully to improve rigidity in Peyronie’s disease patients. It should be recognized though that a much stronger erection with curvature may have a greater risk of being reinjured during sex and make the deformity worse. But this has not been reported. The use of the L-arginine is as an anti-fibrotic (i.e. anti-scarring) agent. It should be taken daily and the recommended dose is 1000 mg twice per day. Viagra, Levitra, and Cialis are taken on an as-needed basis, but can be taken up to once per day. There is experimental evidence to suggest that Viagra as well as the other two PDE-5 inhibitors can have some anti-scarring effects as well, but these have not been demonstrated in proper trials.

Previous I am 45, Peyronie’s for 5 years, stable, curve about 75 degrees. I am able to have sexual intercourse, but I worry about getting worse over time. My urologist suggests I take 2 Pentox a day, Is this OK or should I take 3? I also worry about being on the Pentox for years, if I quit after one year will I experience any worsening? Will using Pentox mess with my Immune system? I suffer from lower than normal testosterone, so I get sick easily. Should vitamin D be taken with Pentox to help in immunity?
Next I am a sixty-four year old white male living in the United Kingdom, six foot tall, twelve and a half stone in weight and I consider myself to be in good health. I am not on any medication; I exercise regularly, sleep well, eat healthily and had a good sex-life with my partner. At the end of March 2013 I was diagnosed with Peyronie’s Disease. I have been offered a course of ESWT (Extracorporeal shock wave therapy). My question: This procedure ESWT, how effective is it in treating Peyronie’s Disease, is it too early to do this procedure as it is only been six/seven months since the disease first started and how safe is the ESWT procedure? Many thanks for all the information the association has published, it has helped me enormously to come to terms with the disease.
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