Dr. Levine answers: Peyronie’s disease is a disorder of wound healing with unclear cause. Typically when it occurs, it will be associated with a lump, occasionally pain and deformity. Natural history studies have suggested that about 50% of men who come to see a physician will worsen with time, 40% will the stay the same and 10% will have spontaneous resolution of the deformity. If the deformity completely resolves with disappearance of the plaque scar tissue, it is unlikely that this was Peyronie’s disease and probably just a slow healing wound within the penis.
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